TRIMYRISTIN

Base Information

• Chemical Name: TRIMYRISTIN
• CAS No.: 555-45-3
• Molecular Formula: C45H86O6
• Molecular Weight: 723.174
• Hs Code.: 29159000
• European Community (EC) Number: 209-099-7
• NSC Number: 4062
• UNII: 18L31PSR28
• DSSTox Substance ID: DTXSID701014651
• Nikkaji Number: J6.470J
• Wikipedia: Trimyristin
• Wikidata: Q304581
• NCI Thesaurus Code: C84229
• RXCUI: 1368882
• Metabolomics Workbench ID: 8971
• Mol file: 555-45-3.mol

Synonyms:Myristin,tri- (8CI);Tetradecanoic acid, 1,2,3-propanetriyl ester (9CI);Dynasan 114;Glycerin trimyristate;Glycerol trimyristate;Glyceryl trimyristate;Glyceryltritetradecanoate;Myristic acid triglyceride;Myristic triglyceride;NSC 4062;Triglyceride MMM;Trimyristin;Trimyristoylglycerol;Tritetradecanoin;VP 114;

Chemical Property of TRIMYRISTIN

Chemical Property:

• Appearance/Colour: white to light beige crystalline powder
• Vapor Pressure: 1.23E-19mmHg at 25°C
• Melting Point: 56-57 °C(lit.)
• Refractive Index: 1.463
• Boiling Point: 703.5 °C at 760 mmHg
• Flash Point: 270.9 °C
• PSA: 78.90000
• Density: 0.924 g/cm³
• LogP: 14.08790
• Storage Temp.: -20°C
• Water Solubility.: Insoluble in water. Soluble in chloroform, ether, ethanol or dichloromethane
• XLogP3: 18.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 44
• Exact Mass: 722.64244046
• Heavy Atom Count: 51
• Complexity: 711

Purity/Quality:

99.9% ^*data from raw suppliers

Glycerol Tritetradecanoate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Biological Agents -> Plant Oils and Extracts
• Canonical SMILES: CCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC
• Uses: Trimyristin, is the triglyceride of myristic acid, which is found naturally in many vegetable fats and oils. It can be used for the preparation of Solid lipid nanoparticles (SLN) composed of trimyristin (solid lipid) and poloxamer 407 (surfactant).

Technology Process of TRIMYRISTIN

There total 5 articles about TRIMYRISTIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

n-tetradecanoic acid (544-63-8) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → tritetradecanoylglycerol (555-45-3)

Guidance literature:

n-tetradecanoic acid; glycerol; With sulfuric acid; at 119.84 ℃; for 3h;

In chloroform; at 69.84 ℃; for 0.5h;

DOI:10.3390/molecules23123141

Reference yield:

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) + tetradecanoyl chloride (112-64-1) → tritetradecanoylglycerol (555-45-3)

Guidance literature:

With pyridine;

Reference yield:

1,2,3-trichloropropane (96-18-4) + potassium myristate (13429-27-1) → tritetradecanoylglycerol (555-45-3)

Guidance literature:

at 160 ℃;

upstream raw materials:

1,2,3-trichloropropane

potassium myristate

n-tetradecanoic acid

glycerol

Downstream raw materials:

n-tetradecanoic acid

glycerol 1,3-dimyristate

methyl myristoate

1-Tetradecanol

Refernces

• 1、 -. "MALLEABLE, BIODEGRADABLE HEMOSTATIC AGENT". . . Retrieved 2012/10/18.
• 2、 Omar, Ibrahim Che,Nishio, Naomichi,Nagai, Shiro. "Fat Hydrolysis and Esterification by a Lipase from Humicola lanuginosa". . p. 2153 - 2160. Retrieved 2007/10/02.