Technology Process of 3-Hydroxy-7-methoxy-1-pentyl-9-propyldibenzo[b,d]furan-2-carboxylic acid
There total 10 articles about 3-Hydroxy-7-methoxy-1-pentyl-9-propyldibenzo[b,d]furan-2-carboxylic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
boron trichloride;
In
dichloromethane;
for 21h;
Ambient temperature;
- Guidance literature:
-
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
ethyl acetate;
for 12h;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 35 percent / SO2Cl2 / diethyl ether / 2 h / Ambient temperature
2: 1.) 15percent aq. NaOH, 2.) conc. HCl / 1.) reflux, 3 h, 2.) reflux, 10 min
3: K2CO3 / acetone / 10 h
4: 83 percent / I2, HgO / diethyl ether / 24 h / Ambient temperature
5: 44 percent / Cu / 12 h / 205 °C
6: aq. HBr / acetic acid / 1.) reflux, 5 h, 2.) 185 deg C, 3 h
7: K2CO3 / acetone / 6 h
8: 1.) TiCl4, 2.) NaClO2, resorcinol, AcONa, AcOH, 3.) BF3
With
hydrogenchloride; sodium hydroxide; sodium chlorite; sulfuryl dichloride; boron trifluoride; hydrogen bromide; iodine; sodium acetate; titanium tetrachloride; copper; potassium carbonate; acetic acid; mercury(II) oxide; recorcinol;
In
diethyl ether; acetic acid; acetone;