threo-1-(4-Hydroxy- 3-Methoxyphenyl)propane-1,2-diol

Base Information

• Chemical Name: threo-1-(4-Hydroxy- 3-Methoxyphenyl)propane-1,2-diol
• CAS No.: 848031-94-7
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.219
• Mol file: 848031-94-7.mol

Synonyms:

Chemical Property of threo-1-(4-Hydroxy- 3-Methoxyphenyl)propane-1,2-diol

Chemical Property:

• PSA: 69.92000
• LogP: 0.81500

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

threo-1-(4-Hydroxy-3-methoxyphenyl)propane-1,2-diol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of threo-1-(4-Hydroxy- 3-Methoxyphenyl)propane-1,2-diol

There total 10 articles about threo-1-(4-Hydroxy- 3-Methoxyphenyl)propane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C17H20O4 → 1-(4-hydroxy-3-methoxyphenyl)propan-1,2-diol (24762-60-5,848031-94-7)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h;

Reference yield:

2-methoxy-4-propenylphenol (97-54-1) → 4-allylguaiacol (97-53-0) + 1-(4-hydroxy-3-methoxyphenyl)2-propanone (2503-46-0) + 1-(4-hydroxy-3-methoxyphenyl)propan-1,2-diol (24762-60-5,848031-94-7) + C20H22O4 + vanillin (121-33-5,8014-42-4)

Guidance literature:

With dihydrogen peroxide; In water; acetonitrile; at 169 ℃; for 0.0366667h; under 12463.6 Torr; Temperature; Reagent/catalyst; Pressure; Catalytic behavior; Irradiation;

DOI:10.1039/c7gc01405h

Reference yield:

curcumin (458-37-7) → threo-1-(3-methoxy-4-hydroxy-phenyl)-propan-1,2-diol (848031-94-7) + erythro-1-(3-methoxy-4-hydroxy-phenyl)-propan-1,2-diol (848031-94-7) + curculactone B + curculactone A + 3-methoxy-4-hydroxybenzoic acid (121-34-6) + vanillin (121-33-5,8014-42-4)

Guidance literature:

In methanol; at 20 ℃; γ-irradiation;

DOI:10.1016/j.bmcl.2010.12.122

upstream raw materials:

2-methoxy-4-propenylphenol

(E)-2-methoxy-4-(1-propenyl)phenol

(E)-2-methoxy-1-(phenylmethoxy)-4-(prop-1-en-1-yl)benzene

curcumin

Downstream raw materials:

1-[3-methoxy-4-(4-nitro-benzoyloxy)-phenyl]-1,2-bis-(4-nitro-benzoyloxy)-propane

Refernces

• 1、 Filiciotto, Layla,Balu, Alina M.,Romero, Antonio A.,Rodríguez-Castellón, Enrique,Van Der Waal, Jan C.,Luque, Rafael. "Benign-by-design preparation of humin-based iron oxide catalytic nanocomposites". . p. 4423 - 4434. Retrieved 2017/09/27.
• 2、 Kim, Tae Hoon,Kim, Jae Kyung,Ito, Hideyuki,Jo, Cheorun. "Enhancement of pancreatic lipase inhibitory activity of curcumin by radiolytic transformation". experimental part. p. 1512 - 1514. Retrieved 2011/04/22.