Eprazinone

Base Information

• Chemical Name: Eprazinone
• CAS No.: 10402-90-1
• Molecular Formula: C24H32N2O2
• Molecular Weight: 380.53
• Hs Code.: 2933599090
• European Community (EC) Number: 233-873-3
• UNII: 883YNL63WU
• DSSTox Substance ID: DTXSID1048336
• Nikkaji Number: J9.811F
• Wikipedia: Eprazinone
• Wikidata: Q389207
• NCI Thesaurus Code: C65518
• Metabolomics Workbench ID: 152064
• ChEMBL ID: CHEMBL1885437
• Mol file: 10402-90-1.mol

Synonyms:1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzyloxy)propylpiperazine;1-(2-phenyl-2-ethoxy)ethyl-4-(3-phenyl-2-methyl-3-propanone)piperazine;3-(4-(beta-ethoxyphenethyl)-1-piperazinyl)-2-methylpropiophenone;746 CE;Eftapan;eprazinone;eprazinone dihydrochloride;eprazinone dihydrochloride, 3-(14)C-labeled;eprazinone hydrochloride

Chemical Property of Eprazinone

Chemical Property:

• Refractive Index: 1.579
• Boiling Point: 503.9 °C at 760 mmHg
• PKA: 6.83±0.10(Predicted)
• Flash Point: 258.5 °C
• PSA: 32.78000
• Density: 1.064 g/cm³
• LogP: 3.77660
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 380.246378268
• Heavy Atom Count: 28
• Complexity: 450

Purity/Quality:

99% ^*data from raw suppliers

Eprazinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
• Therapeutic Function: Antitussive

Technology Process of Eprazinone

There total 1 articles about Eprazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

1-(2-Ethoxy-2-phenylethyl)piperazine dihydrochloride (54749-87-0) + 1-phenyl-propan-1-one (93-55-0) → eprazinone (10402-90-1)

Guidance literature:

With hydrogenchloride; for 5h; Heating;

DOI:10.1135/cccc19832977

upstream raw materials:

1-(2-Ethoxy-2-phenylethyl)piperazine dihydrochloride

1-phenyl-propan-1-one

Refernces