(1,1-Dimethylethyl)phenylphosphinic chloride

Base Information

• Chemical Name: (1,1-Dimethylethyl)phenylphosphinic chloride
• CAS No.: 4923-85-7
• Molecular Formula: C10H14ClOP
• Molecular Weight: 216.647
• DSSTox Substance ID: DTXSID80964191
• Nikkaji Number: J832.043H
• Mol file: 4923-85-7.mol

Synonyms:4923-85-7;(1,1-DIMETHYLETHYL)PHENYLPHOSPHINIC CHLORIDE;SCHEMBL14246523;DTXSID80964191;tert-Butylchlorophenylphosphine oxide;tert-Butyl(phenyl)phosphinic chloride;TERT-BUTYL(PHENYL)PHOSPHINOYL CHLORIDE;Phosphinic chloride, (1,1-dimethylethyl)phenyl-;EN300-37380838

Chemical Property of (1,1-Dimethylethyl)phenylphosphinic chloride

Chemical Property:

• Vapor Pressure: 0.000312mmHg at 25°C
• Boiling Point: 330.8°Cat760mmHg
• Flash Point: 153.9°C
• Density: 1.11g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 216.0470798
• Heavy Atom Count: 13
• Complexity: 214

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)P(=O)(C1=CC=CC=C1)Cl

Technology Process of (1,1-Dimethylethyl)phenylphosphinic chloride

There total 11 articles about (1,1-Dimethylethyl)phenylphosphinic chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

S-methyl tert-butylphenylphosphinothiolate (76380-86-4) → tert-butylphenylphosphinic acid chloride (4923-85-7)

Guidance literature:

With chlorine; In tetrachloromethane; for 1.5h; Ambient temperature;

DOI:10.1021/jo00372a019

Reference yield: 75.0%

tertiary butyl chloride (507-20-0) + Dichlorophenylphosphine (644-97-3) → tert-butylphenylphosphinic acid chloride (4923-85-7)

Guidance literature:

With aluminium trichloride;

DOI:10.1080/10426509608037973

Reference yield:

S-methyl tert-(butylphenylphosphino)thiolate (51584-29-3,51584-30-6,76380-86-4) → (S)-(-)-tert-butylphenylphosphinic chloride (75213-01-3,75213-02-4) + C10H14ClOP (4923-85-7,63246-16-2,75213-01-3,75213-02-4)

Guidance literature:

With sulfuryl dichloride; (-)-S-methyl tert-(butylphenylphosphino)thiolate; In benzene;

DOI:10.1021/ja00541a047

upstream raw materials:

tert-butylchlorophenylphosphane

S-methyl tert-butylphenylphosphinothiolate

P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester

isobutene

Downstream raw materials:

t-butyl(phenyl)phosphinic acid

t-butyl(phenyl)phosphinic azide

tert.-butyl-phenylthiophosphinic chloride

Refernces

• 1、 Maier, Ludwig,Diel, Peter J.. "Organic phosphorus compounds 106.1 a 31P-NMR study of phosphinous-, phosphinic-, and thiophosphinic amides". . p. 273 - 300. Retrieved 2007/10/03.
• 2、 Kowalski, Jozef,Wozniak, Lucyna,Chojnowski, Julian. "SILYLPEROXIDES AS SELECTIVE OXYGENATION REAGENTS IN PHOSPHORUS CHEMISRTY". . p. 125 - 128. Retrieved 2007/10/02.