Biurea

Base Information

• Chemical Name: Biurea
• CAS No.: 110-21-4
• Deprecated CAS: 77107-48-3
• Molecular Formula: C2H6 N4 O2
• Molecular Weight: 118.095
• Hs Code.: 29280000
• European Community (EC) Number: 203-747-2
• NSC Number: 1897
• UNII: POJ4UOY01H
• DSSTox Substance ID: DTXSID6024628
• Nikkaji Number: J2.447C
• Wikipedia: Biurea
• Wikidata: Q4919204
• ChEMBL ID: CHEMBL3188383
• Mol file: 110-21-4.mol

Synonyms:Biurea;110-21-4;hydrazine-1,2-dicarboxamide;1,2-HYDRAZINEDICARBOXAMIDE;Ureidourea;(carbamoylamino)urea;Bicarbamamide;Bicarbamimidic acid;Hydrazodicarbonamide;Hydrazodicarboxamide;Hydradicarbonamide;Hydrazocarbonamide;Urea, ureido-;Pseudourea, 3-ureido-;N,N'-Dicarbamoylhydrazine;Semicarbazide, 1-carbamoyl-;Ureidoureacarboxamide;N,N'-Biscarbamoylhydrazine;1,1-Hydrazoformamide;Hydrazinedicarboxylic acid diamide;Formimidic acid, 1-semicarbazido-;Semicarbazide, 1-(1-hydroxyformimidoyl)-;1,1'-Hydrazobis(formamide);Hydrazine, 1,2-bis(aminocarbonyl)-;Hydrazine, 1,2-dicarbamoyl-;Formamide, 1,1'-hydrazobis-;Bicarbamimidic acid (VAN);NSC 1897;Hydrazinecarboximidic acid, 2-(aminocarbonyl)-;CCRIS 5976;HSDB 5014;EINECS 203-747-2;UNII-POJ4UOY01H;POJ4UOY01H;AI3-28537;DTXSID6024628;NSC-1897;Diharnstoff;Hydrazodiformamide;Hydrazine,2-dicarbamoyl-;Formamide,1'-hydrazobis-;1,1'-Hydrazinebisformamide;N,N\'-Dicarbamoylhydrazine;SCHEMBL21785;DTXCID404628;CHEMBL3188383;SCHEMBL22821618;Hydrazine,2-bis(aminocarbonyl)-;NSC1897;Tox21_300989;LS-502;MFCD00025398;STL281876;AKOS005174048;SB86000;HYDRAZINE-N,N'-BIS(CARBOXAMIDE);NCGC00248246-01;NCGC00254891-01;AS-59029;CAS-110-21-4;1,2-HYDRAZINEDICARBOXAMIDE [HSDB];B0512;CS-0149929;FT-0606465;FT-0669251;D81814;EN300-7413859;Q-200731;Q4919204;77107-48-3

Chemical Property of Biurea

Chemical Property:

• Appearance/Colour: WHITE POWDER
• Vapor Pressure: 0.000165mmHg at 25°C
• Melting Point: 247-250 °C
• Refractive Index: 1.61
• Boiling Point: °Cat760mmHg
• PKA: 10.06±0.43(Predicted)
• Flash Point: °C
• PSA: 110.24000
• Density: 1.461g/cm³
• LogP: 0.42040
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Sulfuric Acid (Sparingly, Heated)
• XLogP3: -2.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 118.04907545
• Heavy Atom Count: 8
• Complexity: 96.6

Purity/Quality:

99%+ ^*data from raw suppliers

Biurea ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: C(=O)(N)NNC(=O)N
• Uses: Hydrazine-1,2-dicarboxamide is a useful compound in the process of producing protected anode active material particles for rechargeable lithium batteries.

Technology Process of Biurea

There total 150 articles about Biurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Azodicarboxamid (123-77-3,97707-96-5) → hydrazodicarboxamide (110-21-4)

Guidance literature:

With hydrazine hydrate; In acetonitrile; at 20 ℃; for 1.5h;

DOI:10.1016/j.tetlet.2008.03.083

Reference yield: 97.0%

sodium chlorobiuret salt → hydrazodicarboxamide (110-21-4)

Guidance literature:

With ammonia; aluminum (III) chloride; zinc(II) chloride; In water; at 10 - 60 ℃; for 1h;

Reference yield: 96.0%

BIURET (108-19-0,1866-97-3) → hydrazodicarboxamide (110-21-4)

Guidance literature:

BIURET; With sodium hypochlorite; In water; at 5 - 10 ℃;

With ammonia; zinc(II) chloride; In water; at 100 ℃; for 0.5h; Product distribution / selectivity;

upstream raw materials:

acetophenone semicarbazone

bromocyane

phorone

semicarbazide hydrochloride

Downstream raw materials:

4-(4-methylphenyl)-1,2,4-triazolidine-3,5-dione

4-o-tolyl-[1,2,4]triazolidine-3,5-dione

4-methylurazole

4-ethyl-[1,2,4]triazolidine-3,5-dione

Refernces

• 1、 Audrieth, L. F.. "". . p. 1250 - 1251. Retrieved 1930.
• 2、 Kirilin,Belova,Knyazev,Lega,Petrov,Chernyshev. "Organosilyl isocyanates. Reactions with hydrazine, 1,1-dimethylhydrazine, and 1-methyl-1-[2-(1-methylhydrazino)ethyl]hydrazine and structural and electronic characteristics". . p. 1930 - 1934. Retrieved 2005.
• 3、 Koppes, William M.,Moran, Jesse S.,Oxley, Jimmie C.,Smith, James L.. "Azo bond hydrogenation with hydrazine, R-NHNH2, and hydrazobenzene". . p. 3234 - 3237. Retrieved 2008.
• 4、 Grove et al.. "". . p. 4131,4132. Retrieved 1961.
• 5、 Mashima. "". . p. 974,975. Retrieved 1964.
• 6、 De Souza, Rodrigo O.M.A.,Da Penha, Eduardo T.,Milagre, Humberto M.S.,Garden, Simon J.,Esteves, Pierre M.,Eberlin, Marcos N.,Antunes, Octavio A.C.. "The three-component biginelli reaction: A combined experimental and theoretical mechanistic investigation". supporting information; body text. p. 9799 - 9804. Retrieved 2010/05/19.