Diethyl n,s-ditritylcysteinylglutamate

Base Information

• Chemical Name: Diethyl n,s-ditritylcysteinylglutamate
• CAS No.: 35959-82-1
• Molecular Formula: C50H50N2O5S
• Molecular Weight: 791.0074
• NSC Number: 127739
• DSSTox Substance ID: DTXSID50299048
• Mol file: 35959-82-1.mol

Synonyms:35959-82-1;diethyl n,s-ditritylcysteinylglutamate;NSC127739;DTXSID50299048;NSC-127739

Chemical Property of Diethyl n,s-ditritylcysteinylglutamate

Chemical Property:

• Vapor Pressure: 1.31E-29mmHg at 25°C
• Boiling Point: 855.7°Cat760mmHg
• Flash Point: 471.3°C
• Density: 1.177g/cm³
• XLogP3: 10
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 21
• Exact Mass: 790.34404387
• Heavy Atom Count: 58
• Complexity: 1130

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CCC(C(=O)OCC)NC(=O)C(CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Technology Process of Diethyl n,s-ditritylcysteinylglutamate

There total 1 articles about Diethyl n,s-ditritylcysteinylglutamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl-L-glutamate hydrochloride (1118-89-4) + N,S-ditrityl-L-cysteine diethhylamine (27486-88-0) → (S)-2-[(R)-2-(Trityl-amino)-3-tritylsulfanyl-propionylamino]-pentanedioic acid diethyl ester (35959-82-1)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1021/jm00271a005

upstream raw materials:

diethyl-L-glutamate hydrochloride

N,S-ditrityl-L-cysteine diethhylamine

Refernces