Technology Process of Indeno[1,2,3-de]quinoline
There total 7 articles about Indeno[1,2,3-de]quinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; cesium pivalate; bis-diphenylphosphinomethane;
In
N,N-dimethyl-formamide;
at 110 ℃;
for 60h;
DOI:10.1021/jo048788h
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 63 percent / PPh3; DEAD / tetrahydrofuran / 4 h / 0 - 20 °C
2: 80 percent / ICl / CH2Cl2 / 1 h / -78 °C
3: 92 percent / NaOH; O2 / ethanol / 12 h / 50 °C / 760 Torr
4: 54 percent / 1,1-bis(diphenylphosphino)methane; CsO2CCMe3; Pd(OAc)2 / dimethylformamide / 60 h / 110 °C
With
palladium diacetate; sodium hydroxide; oxygen; Iodine monochloride; triphenylphosphine; cesium pivalate; bis-diphenylphosphinomethane; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo048788h
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 63 percent / PPh3; DEAD / tetrahydrofuran / 4 h / 0 - 20 °C
2: 80 percent / ICl / CH2Cl2 / 1 h / -78 °C
3: 92 percent / NaOH; O2 / ethanol / 12 h / 50 °C / 760 Torr
4: 54 percent / 1,1-bis(diphenylphosphino)methane; CsO2CCMe3; Pd(OAc)2 / dimethylformamide / 60 h / 110 °C
With
palladium diacetate; sodium hydroxide; oxygen; Iodine monochloride; triphenylphosphine; cesium pivalate; bis-diphenylphosphinomethane; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo048788h
