Benzene-1,2,3,4-tetracarboxylic acid

Base Information

• Chemical Name: Benzene-1,2,3,4-tetracarboxylic acid
• CAS No.: 476-73-3
• Molecular Formula: C10H6 O8
• Molecular Weight: 254.153
• European Community (EC) Number: 207-510-4
• DSSTox Substance ID: DTXSID10197218
• Nikkaji Number: J95.745C
• Wikidata: Q60817295
• Mol file: 476-73-3.mol

Synonyms:Benzene-1,2,3,4-tetracarboxylic acid;476-73-3;1,2,3,4-benzenetetracarboxylic acid;EINECS 207-510-4;MELLOPHANIC ACID;Benzenetetracarboxylic acid;benzene-1,2,3,4-tetracarboxylicacid;SCHEMBL22989;DTXSID10197218;AKOS000277259;1,2,3,4-Benzene-tetracarboxylic acid;EN300-1654149;J-503748;Q60817295

Chemical Property of Benzene-1,2,3,4-tetracarboxylic acid

Chemical Property:

• Vapor Pressure: 6.24E-14mmHg at 25°C
• Melting Point: 264-267℃ (decomposition)
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 572.2°Cat760mmHg
• PKA: pK1: 2.05;pK2: 3.25;pK3: 4.73;pK4: 6.21 (25°C)
• Flash Point: 313.9°C
• PSA: 149.20000
• Density: 1.821g/cm³
• LogP: 0.47940
• XLogP3: 0
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 254.00626715
• Heavy Atom Count: 18
• Complexity: 363

Purity/Quality:

98%,99%, ^*data from raw suppliers

Benzene-1,2,3,4-tetracarboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1C(=O)O)C(=O)O)C(=O)O)C(=O)O

Technology Process of Benzene-1,2,3,4-tetracarboxylic acid

There total 86 articles about Benzene-1,2,3,4-tetracarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2,3,7,8-tetrahydro-2,7-diethylbenzo<1,2-c:3,4-c'>dipyrrole-1,6-dione (85068-01-5) → 1,2,3,4-benzenetetracaboxylic acid (476-73-3)

Guidance literature:

With nitric acid; at 140 ℃; for 4h;

DOI:10.1021/jo00158a020

Reference yield: 85.0%

1,2,3,4,5,6,7,8-Octahydrophenanthrene (5325-97-3) → 1,2,3,4-benzenetetracaboxylic acid (476-73-3)

Guidance literature:

With potassium permanganate; manganese(II) sulfate tetrahydrate; sodium 4-dodecylbenzenesulfonate; In water; at 95 ℃; for 50h; Pressure; Temperature; Solvent; Reagent/catalyst; Time;

Reference yield: 75.0%

1,2,3,4-Tetramethylbenzene (488-23-3) → 1,2,3,4-benzenetetracaboxylic acid (476-73-3)

Guidance literature:

With cerium(III) chloride; 1,1,1-trichloroethanol; oxygen; In acetonitrile; at 60 ℃; Irradiation;

DOI:10.1007/s11426-021-1032-7

upstream raw materials:

3,6-dimethyl phthalic anhydride

3-isopropyl-6-methyl-phthalic acid anhydride

1,2,3,4-Tetramethylbenzene

1,4-dimethylnaphthalene

Downstream raw materials:

1,2,3,4-Tetramethylbenzene

Refernces

• 1、 Takahashi. "". . p. 265. Retrieved 1968.
• 2、 Wang, Chang-Cheng,Zhang, Guo-Xiang,Zuo, Zhi-Wei,Zeng, Rong,Zhai, Dan-Dan,Liu, Feng,Shi, Zhang-Jie. "Photo-induced deep aerobic oxidation of alkyl aromatics". . p. 1487 - 1492. Retrieved 2021/07/10.
• 3、 -. "PROCESS FOR PRODUCING 1,2,3,4-BENZENETETRACARBOXYLIC ACID". Page/Page column 5. . Retrieved 2009/12/28.