2-Ethoxy-3,4-dihydro-2H-pyran

Base Information

• Chemical Name: 2-Ethoxy-3,4-dihydro-2H-pyran
• CAS No.: 103-75-3
• Deprecated CAS: 126753-01-3
• Molecular Formula: C7H12O2
• Molecular Weight: 128.171
• Hs Code.: 29329990
• European Community (EC) Number: 203-141-8
• NSC Number: 6271
• UN Number: 3271
• UNII: K6DS120547
• DSSTox Substance ID: DTXSID40883293
• Nikkaji Number: J51.178A
• Wikidata: Q27282010
• Mol file: 103-75-3.mol

Synonyms:2-Ethoxy-3,4-dihydro-2H-pyran;103-75-3;2-Ethoxypyran;2H-Pyran, 2-ethoxy-3,4-dihydro-;2-Ethoxydihydropyran;2-Ethoxy-3,4-dihydropyran;ETHOXYDIHYDROPYRAN;3,4-Dihydro-2-ethoxy-2H-pyran;2-Ethoxy-3,4-dihydro-2-pyran;2-Ethoxy-2,3-dihydro-4H-pyran;2-Ethoxy-3,4-dihydro-1,2-pyran;2-Ethoxy-2,3-dihydro(4H)pyran;3,4-Dihydro-2H-pyran-2-yl ethyl ether;3,4-dihydro-2-ethoxy-2H-pyrane;NSC 6271;HSDB 2839;2-Ethoxy-2,3-dihydro-gamma-pyran;EINECS 203-141-8;2-Ethoxy-2,3-dihydro-.gamma.-pyran;BRN 0109855;AI3-24750;UNII-K6DS120547;NSC-6271;K6DS120547;5-17-03-00196 (Beilstein Handbook Reference);2-Ethoxy-2,3-dihydro[4H]pyran;2-Ethoxy-3,2-pyran;WLN: T6O BUTJ FO2;SCHEMBL379887;DTXSID40883293;NSC6271;2-thoxy-3,4-dihydro-2H-pyrane;3,4-DIHYDRO-2-ETHOXYPYRAN;BBL027595;MFCD00006561;STK802314;AKOS009031552;3,4-Dihydro-2-ethoxy-2H-pyran, 98%;AS-31061;LS-127314;CS-0076531;E0529;FT-0631561;EN300-20557;2-ETHOXY-3,4-DIHYDRO-2-PYRAN [HSDB];A800800;2-ETHOXY-3,4-DIHYDRO-2H-PYRAN, (+/-)-;3,4-DIHYDRO-2-ETHOXY-2H-PYRAN, (+/-)-;Q27282010;F0001-0080;Z104478848

Chemical Property of 2-Ethoxy-3,4-dihydro-2H-pyran

Chemical Property:

• Appearance/Colour: colorless liquid
• Vapor Pressure: 0.811mmHg at 25°C
• Melting Point: 153-155 °C
• Refractive Index: n20/D 1.439(lit.)
• Boiling Point: 144.8 °C at 760 mmHg
• Flash Point: 24.4 °C
• PSA: 18.46000
• Density: 0.96 g/cm³
• LogP: 1.67310
• Storage Temp.: 2-8°C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 128.083729621
• Heavy Atom Count: 9
• Complexity: 99.1
• Transport DOT Label: Flammable Liquid

Purity/Quality:

98% ^*data from raw suppliers

2-Ethoxy-3,4-dihydro-2H-pyran >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,F
• Statements: 10-36/38-11
• Safety Statements: 26-16

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Ethers, Other
• Canonical SMILES: CCOC1CCC=CO1
• Uses: Stabilizer, intermediate.

Technology Process of 2-Ethoxy-3,4-dihydro-2H-pyran

There total 2 articles about 2-Ethoxy-3,4-dihydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl vinyl ether (109-92-2,25104-37-4) + acrolein (107-02-8,25068-14-8) → 2-ethoxy-2,3-dihydro-4H-pyran (103-75-3)

Guidance literature:

tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato)ytterbium; for 24h; Ambient temperature;

DOI:10.1016/S0040-4039(01)80009-5

Reference yield:

→ 2-ethoxy-2,3-dihydro-4H-pyran (103-75-3)

Guidance literature:

Acrolein, Ethylvinylether (4), erhitzen unter Druck;

Reference yield: 99.0%

2-ethoxy-2,3-dihydro-4H-pyran (103-75-3) → 2-ethoxytetrahydropyran (4819-83-4)

Guidance literature:

With fac-[Mn(1,2-bis(di-isopropylphosphino)ethane)(CO)₃(CH₂CH₂CH₃)]; hydrogen; In diethyl ether; at 60 ℃; for 24h; under 37503.8 Torr;

DOI:10.1021/acscatal.9b03963

upstream raw materials:

ethyl vinyl ether

acrolein

Downstream raw materials:

Glutaraldehyde

glutaraldehyde bis-(2,4-dinitro-phenylhydrazone)

diethyl Fumarate

Diethyl maleate

Refernces

• 1、 Veselovskii, V. V.,Gybin, A. S.,Lozanova, A. V.,Moiseenkov, A. M.,Smit, V. A.. "EFFICIENT CYCLOADDITION DURING ADSORPTION ON CHROMATOGRAPHIC SOLVENTS". . p. 94 - 100. Retrieved 2007/10/02.
• 2、 Malanga, C.,Menicagli, R.,Innocenti, M. Dell',Lardicci, L.. "A NEW APPROACH TO δ-LACTONES, RELATED TO THE PRELOG-DJERASSI LACTONE.". . p. 239 - 240. Retrieved 2007/10/02.