GLYCYRRHIZIC ACID AMMONIUM SALT

Base Information

• Chemical Name: GLYCYRRHIZIC ACID AMMONIUM SALT
• CAS No.: 1407-03-0
• Molecular Formula: C42H65NO16
• Molecular Weight: 839.96
• Mol file: 1407-03-0.mol

Synonyms:GLYCAMIL;GLYCYRRHIZIC ACID, NH4;GLYCYRRHIZIC ACID, NH4+;AMMONIATED GLYCYRRHIZIN;GLYCYRRHIZIN AMMONIACAL;GLYCYRRHIZIN, AMMONIATED;AMMONIUM GLYCYRRHIZINATE;GLYCYRRHIZIN AMMONIUM SALT;MONOAMMONIUM GLYCRRHIZINATE;MONOAMMONIUM GLYCYRRHIZINATE;

Chemical Property of GLYCYRRHIZIC ACID AMMONIUM SALT

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 971.4oC at 760 mmHg
• Flash Point: 288.1oC
• PSA: 270.28000
• LogP: 2.56950
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Sparingly), Ethanol (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

99% ^*data from raw suppliers

AmmoniumGlycyrrhizinate(AMGZ) >99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: ammonium glycyrrhizinate is a conditioner, it is also used as a flavoring agent, particularly for lipsticks.

Technology Process of GLYCYRRHIZIC ACID AMMONIUM SALT

There total 1 articles about GLYCYRRHIZIC ACID AMMONIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

→ Glycyrrhizin ammonium (53956-04-0,1407-03-0)

Guidance literature:

Reference yield:

glycyrrhizinic acid ammonium salt (1407-03-0) → C42H62O16*H3N

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide / water / 8 h / Reflux

1.2: 1.5 h / 20 °C

2.1: ammonium hydroxide / ethanol

With ammonium hydroxide; potassium hydroxide; In ethanol; water;

DOI:10.1007/s11418-021-01589-9

Reference yield:

nicotinic acid (59-67-6) + glyccyrham (1407-03-0) → C54H68N2O18

Guidance literature:

With pyridine; phosphorus pentachloride; Yield given. Multistep reaction; 1.) a) 30 deg C, 1 h, b) 40-45 deg C, 1 h, 2.) a) 50 deg C, 3 h, b) RT, overnight;

Refernces