Technology Process of 2-(6-phenylpyridin-2-yl)acetonitrile
There total 3 articles about 2-(6-phenylpyridin-2-yl)acetonitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium carbonate; triphenylphosphine;
In
methanol; toluene;
at 80 ℃;
for 24h;
Inert atmosphere;
DOI:10.1002/jhet.1535
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 80 °C / Inert atmosphere
1.2: pH 1 / Inert atmosphere; Cooling with ice
2.1: toluene-4-sulfonic acid / toluene / 12 h / Reflux
3.1: sodium carbonate; triphenylphosphine / toluene; methanol / 24 h / 80 °C / Inert atmosphere
With
sodium carbonate; potassium carbonate; toluene-4-sulfonic acid; triphenylphosphine;
In
methanol; N,N-dimethyl-formamide; toluene;
3.1: |Suzuki Coupling;
DOI:10.1002/jhet.1535
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / toluene / 12 h / Reflux
2: sodium carbonate; triphenylphosphine / toluene; methanol / 24 h / 80 °C / Inert atmosphere
With
sodium carbonate; toluene-4-sulfonic acid; triphenylphosphine;
In
methanol; toluene;
2: |Suzuki Coupling;
DOI:10.1002/jhet.1535