DL-3-Aminobutyric acid

Base Information

• Chemical Name: DL-3-Aminobutyric acid
• CAS No.: 2835-82-7
• Molecular Formula: C4H9NO2
• Molecular Weight: 103.121
• Hs Code.: 2922499990
• Mol file: 2835-82-7.mol

Synonyms:3-AMINOBUTANOIC ACID;3-Methyl-b-alanine;RS-3-aminobutanoic acid;Butanoic acid, 3-amino-, (±)-;RARECHEM AK HD C012;DL-BABA;3-AMINOBUTYLIC ACID;3-Aminobutyric acid;

Chemical Property of DL-3-Aminobutyric acid

Chemical Property:

• Appearance/Colour: White powder.
• Vapor Pressure: 0.0352mmHg at 25°C
• Melting Point: 189-191oC (dec.)
• Refractive Index: 1.4650 (estimate)
• Boiling Point: 223.6oC at 760 mmHg
• PKA: pK2: 10.14(0) (25°C)
• Flash Point: 89oC
• PSA: 63.32000
• Density: 1.105g/cm3
• LogP: 0.50860
• Solubility.: soluble
• Water Solubility.: soluble

Purity/Quality:

99.0% ^*data from raw suppliers

3-Aminobutanoic acid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-24/25-22-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-3-Aminobutyric acid

There total 40 articles about DL-3-Aminobutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)butyric acid (4443-37-2) → 3-aminobutyric acid (2835-82-7)

Guidance literature:

With hydrazine; In ethanol; at 110 ℃; for 2.5h;

DOI:10.1021/ja902591g

Reference yield: 96.0%

3-benzylaminobutyric acid (91246-78-5) → 3-aminobutyric acid (2835-82-7)

Guidance literature:

With palladium 10% on activated carbon; ammonium formate; In methanol; at 80 ℃; for 2h; Inert atmosphere;

DOI:10.1039/d1gc00474c

Reference yield: 94.0%

3-methyl-N-(S)-(1-phenylethyl)isoxazolidin-5-one (95503-72-3,95503-73-4,112545-19-4,112692-05-4) → 3-aminobutyric acid (2835-82-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In 1,4-dioxane; at 60 ℃; for 16h;

DOI:10.1016/S0040-4020(01)98811-8

upstream raw materials:

2-methyl-1-pyrrolidine

2-butenoic acid

2-carbamoyl-1-methylethylamine

(E)-but-2-enoic acid

Downstream raw materials:

methyl 3-aminobutyrate

3-Dimethylamino-buttersaeureethylester

(S)-3-Hydroxybutanoic Acid

3-chlorobutyric acid

Refernces

• 1、 Takahashi. "-". . p. 892. Retrieved 1926.
• 2、 Weiner, Barbara,Baeza, Alejandro,Jerphagnon, Thomas,Feringa, Ben L.. "Aldehyde selective Wacker oxidations of phthalimide protected allylic amines: A new catalytic route to β3-amino acids". supporting information; experimental part. p. 9473 - 9474. Retrieved 2009/12/06.