AB 1010 Mesylate

Base Information

• Chemical Name: AB 1010 Mesylate
• CAS No.: 1048007-93-7
• Molecular Formula: C29H34N6O4S2
• Molecular Weight: 594.759
• Mol file: 1048007-93-7.mol

Synonyms:4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)benzamide mesylate;4-(4-methyl-piperazine-1-ylmethyl)-benzoic acid;4-(4-Methylpiperazin-1-ylmethyl)benzoic Acid;Masitinib mesylate;4-(4-carboxybenzyl)-1-methylpiperazine;

Chemical Property of AB 1010 Mesylate

Chemical Property:

• Appearance/Colour: white powder
• PSA: 167.61000
• LogP: 5.21230

Purity/Quality:

98%,99%, ^*data from raw suppliers

Masitinibmesylate >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Masitinib is a novel tyrosine kinases inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, resectively. Masitinib Mesylate can be used to treat sickle cell disease.

Technology Process of AB 1010 Mesylate

There total 1 articles about AB 1010 Mesylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

masitinib (790299-79-5) + methanesulfonic acid (75-75-2,98527-29-8) → Masitinib mesylate (1048007-93-7)

Guidance literature:

In ethanol; at 25 - 70 ℃; for 6h;

upstream raw materials:

masitinib

methanesulfonic acid

Refernces