Pulegol

Base Information

• Chemical Name: Pulegol
• CAS No.: 529-02-2
• Molecular Formula: C10H18O
• Molecular Weight: 154.252
• European Community (EC) Number: 208-448-0
• DSSTox Substance ID: DTXSID60967362
• Nikkaji Number: J11.717J
• Wikidata: Q31190428
• Mol file: 529-02-2.mol

Synonyms:Pulegol;529-02-2;5-methyl-2-(propan-2-ylidene)cyclohexan-1-ol;neoiso-Isopulegol;5-methyl-2-(1-methylethylidene)cyclohexanol;Cyclohexanol, 5-methyl-2-(1-methylethylidene)-;EINECS 208-448-0;5-methyl-2-propan-2-ylidenecyclohexan-1-ol;UNII-H2VTN6VVH7;H2VTN6VVH7;SCHEMBL2684088;DTXSID60967362;AKOS000125963;5-methyl-2-(propan-2-ylidene)cyclohexanol;FT-0697098;EN300-108442;Q67880017

Chemical Property of Pulegol

Chemical Property:

• Vapor Pressure: 0.015mmHg at 25°C
• Boiling Point: 227.6°Cat760mmHg
• Flash Point: 91.3°C
• Density: 0.933g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 166

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCC(=C(C)C)C(C1)O

Technology Process of Pulegol

There total 17 articles about Pulegol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(2-Isopropylidene-5-methyl-cyclohexyloxymethyl)-benzene (158137-71-4) → isopulegol (529-02-2)

Guidance literature:

With 18-crown-6 ether; tert-butylamine; tert-butyl alcohol; potassium; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1055/s-2002-33519

Reference yield: 90.0%

3,7-dimethyl-oct-6-enal (106-23-0,26489-02-1) → 2-[2,6-dimethyl-5-heptenyl]-4,4,8-trimethylhexahydro-1,3-benzodioxine + isopulegol (529-02-2) + p-menthane-3,8-diol (42822-86-6,138663-70-4)

Guidance literature:

sulfuric acid; In water; at 60 ℃; for 7h;

Reference yield: 79.0%

pulegone (89-82-7,3285-04-9,3391-90-0,15932-80-6,90449-51-7) → cis-pulegol (529-02-2,18649-91-7,22472-79-3,22472-80-6,29910-20-1,118760-35-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃;

DOI:10.1016/j.tetasy.2003.08.010

upstream raw materials:

pulegone

ethanol

(2-Isopropylidene-5-methyl-cyclohexyloxymethyl)-benzene

3,7-dimethyl-oct-6-enal

Downstream raw materials:

3,8-p-Menthadien

isoterpinolene

8-methoxy-p-menth-3-ene

1-(1-Ethoxy-1-methyl-ethyl)-4-methyl-cyclohexene

Refernces

• 1、 Song, Shuyan,Liu, Ruixia,Zhang, Yu,Feng, Jing,Liu, Dapeng,Xing, Yan,Zhao, Fengyu,Zhang, Hongjie. "Colloidal noble-metal and bimetallic alloy nanocrystals: A general synthetic method and their catalytic hydrogenation properties". scheme or table. p. 6251 - 6256. Retrieved 2010/07/13.
• 2、 -. "A METHOD OF PRODUCING CYCLIC DIOLS". Page/Page column 14. . Retrieved 2009/12/05.