METHOXYAPIGENINIDIN CHLORIDE, 7-(RG)

Base Information

• Chemical Name: METHOXYAPIGENINIDIN CHLORIDE, 7-(RG)
• CAS No.: 161773-51-9
• Molecular Weight: 304.725
• Mol file: 161773-51-9.mol

Synonyms:METHOXYAPIGENINIDIN CHLORIDE, 7-(RG);7-methoxy Apigenidin (chloride)

Chemical Property of METHOXYAPIGENINIDIN CHLORIDE, 7-(RG)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

98% ^*data from raw suppliers

7-methoxy Apigenidin (chloride) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of METHOXYAPIGENINIDIN CHLORIDE, 7-(RG)

There total 6 articles about METHOXYAPIGENINIDIN CHLORIDE, 7-(RG) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

Acetic acid (S)-2-(4-acetoxy-phenyl)-7-methoxy-chroman-5-yl ester (88607-72-1) → 5-hydroxy-2-(4'-hydroxyphenyl)-7-methoxybenzopyrilium chloride (161773-51-9)

Guidance literature:

With hydrogenchloride; chloranil; In acetic acid; for 1h;

DOI:10.1271/bbb.60.1495

Reference yield:

naringenin (480-41-1) → 5-hydroxy-2-(4'-hydroxyphenyl)-7-methoxybenzopyrilium chloride (161773-51-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / diethyl ether / Ambient temperature

2: 92 percent / pyridine / Ambient temperature

3: 87 percent / sodium borohydride / tetrahydrofuran; ethanol / 2.5 h / Ambient temperature

4: 40 percent / chloranil, conc. HCl / acetic acid / 1 h

With pyridine; hydrogenchloride; sodium tetrahydroborate; chloranil; In tetrahydrofuran; diethyl ether; ethanol; acetic acid;

DOI:10.1271/bbb.60.1495

Reference yield:

(-)-(S)-sakuranetin (520-29-6,2957-21-3,17784-36-0,118244-13-6) → 5-hydroxy-2-(4'-hydroxyphenyl)-7-methoxybenzopyrilium chloride (161773-51-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / pyridine / Ambient temperature

2: 87 percent / sodium borohydride / tetrahydrofuran; ethanol / 2.5 h / Ambient temperature

3: 40 percent / chloranil, conc. HCl / acetic acid / 1 h

With pyridine; hydrogenchloride; sodium tetrahydroborate; chloranil; In tetrahydrofuran; ethanol; acetic acid;

DOI:10.1271/bbb.60.1495

upstream raw materials:

Acetic acid (S)-2-(4-acetoxy-phenyl)-7-methoxy-chroman-5-yl ester

Acetic acid (S)-2-(4-acetoxy-phenyl)-7-methoxy-4-oxo-chroman-5-yl ester

naringenin

(-)-(S)-sakuranetin

Refernces

• 1、 Costantino, Luca,Rastelli, Giulio,Rossi, Maria C.,Albasini, Albano. "Quantitative Measurement of Proton Dissociation and Tautomeric Constants of Apigeninidin". . p. 227 - 234. Retrieved 2007/10/02.