9α,13α-Epidioxyabiet-8(14)-en-18-oic acid

Base Information

• Chemical Name: 9α,13α-Epidioxyabiet-8(14)-en-18-oic acid
• CAS No.: 116499-73-1
• Molecular Formula: C20H30O4
• Molecular Weight: 334.45
• Mol file: 116499-73-1.mol

Synonyms:9α,13α-Epidioxyabiet-8(14)-en-18-oic acid;9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

Chemical Property of 9α,13α-Epidioxyabiet-8(14)-en-18-oic acid

Chemical Property:

• PSA: 55.76000
• LogP: 4.49310

Purity/Quality:

98% ^*data from raw suppliers

9α,13α-Epidioxyabiet-8(14)-en-18-oicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9α,13α-Epidioxyabiet-8(14)-en-18-oic acid

There total 4 articles about 9α,13α-Epidioxyabiet-8(14)-en-18-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H30O3 → 9α,13α-epidioxyabiet-8(14)-en-18-oic acid (116499-73-1)

Guidance literature:

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 20 ℃; for 4h;

DOI:10.1016/j.phytochem.2004.10.017

Reference yield:

palustric acid (1945-53-5) → abieta-8(14)-en-18-oic acid 9α,13α-endoperoxide (5309-35-3,7501-50-0,116499-73-1,133645-20-2)

Guidance literature:

With air; ethanol; Eosin Y;

DOI:10.1007/BF03263120 DOI:10.1021/ja01492a049

Reference yield:

abieto-8(14)-en-18-ol 9α,13α-endoperoxide → 9α,13α-epidioxyabiet-8(14)-en-18-oic acid (116499-73-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium dichromate / CH₂Cl₂ / 5 h / 20 °C

2: NaClO₂; NaH₂PO₄; 2-methyl-2-butene / H₂O; 2-methyl-propan-2-ol / 4 h / 20 °C

With sodium chlorite; sodium dihydrogenphosphate; dipyridinium dichromate; 2-methyl-but-2-ene; In dichloromethane; water; tert-butyl alcohol;

DOI:10.1016/j.phytochem.2004.10.017

upstream raw materials:

palustric acid

ethanol

Refernces