CAPECITABINE-D11

Base Information

• Chemical Name: CAPECITABINE-D11
• CAS No.: 1132662-08-8
• Molecular Formula: C15H13D11FN3O6
• Molecular Weight: 372.43
• Mol file: 1132662-08-8.mol

Synonyms:5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE-D11;CAPECITABINE-D11;5'-Deoxy-5-fluoro-N-[(pentyl-d11-oxy)carbonyl]cytidine;Capecitibine-d11;Capecytabine-d11;Capiibine-d11;Captabin-d11;Ro 09-1978/000-d11

Chemical Property of CAPECITABINE-D11

Chemical Property:

• Melting Point: 45-50°C
• PSA: 126.40000
• LogP: 0.77380
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

97% ^*data from raw suppliers

Capecitabine-d11 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Capecitabine-d11 is intended for use as an internal standard for the quantification of capecitabine by GC- or LC-MS. Capecitabine is a prodrug form of 5-fluorouracil (5-FU). It is converted to 5-FU via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC50s = 97, 578, and 994 μM, respectively) and is inactive in a variety of cancer cell lines, including COLO 205, HCT116, and MCF-7 cells (IC50s = >1,000 μM).
• Uses: An isotopically labelled antineoplastic agent. A prodrug of Doxifluridine (D556750). Capecitabine D11 is an isotopically labelled antineoplastic agent. A prodrug of Doxifluridine.;Labeled Capecitabine, intended for use as an internal standard for the quantification of Capecitabine by GC- or LC-mass spectrometry.