Methanediamine;hydrochloride

Base Information

• Chemical Name: Methanediamine;hydrochloride
• CAS No.: 57166-92-4
• Molecular Formula: CH6 N2 . 2 Cl H
• Molecular Weight: 118.994
• Mol file: 57166-92-4.mol

Synonyms:

Chemical Property of Methanediamine;hydrochloride

Chemical Property:

• Vapor Pressure: 78.1mmHg at 25°C
• Melting Point: >300°C
• Boiling Point: 82.6 °C at 760 mmHg
• Flash Point: °C
• PSA: 52.04000
• Density: 0.879g/cm³
• LogP: 1.86590
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 82.0297759
• Heavy Atom Count: 4
• Complexity: 2.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methylenediamine dihydrochloride ≥99% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(N)N.Cl
• Uses: The Dihydrochloride salt of Methanediamine (M260225) in used in synthesizing FK-506 3’-Methyl Ether (F370010).

Technology Process of Methanediamine;hydrochloride

There total 1 articles about Methanediamine;hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ methylenediamine dihydrochloride (57166-92-4)

Guidance literature:

With hydrogenchloride; at 12 ℃;

Reference yield: 84.0%

n-dodecanoyl chloride (112-16-3) + methylenediamine dihydrochloride (57166-92-4) → N,N'-Methylen-bis-(dodecansaeure-amid) (5136-45-8)

Guidance literature:

With pyridine; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1021/ja0169318

Reference yield: 22.0%

2-methyl-benzyl alcohol (89-95-2) + methylenediamine dihydrochloride (57166-92-4) → N,N'-bis(2-hydroxybenzylidene)-1,1-diaminomethane (3923-68-0)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 0 - 25 ℃;

DOI:10.1002/(sici)1521-3897(199911)341:8<736::aid-prac736>3.0.co;2-v

Downstream raw materials:

(Boc-Phe-Leu-NH-)2CH₂

N,N'-bis(2-hydroxybenzylidene)-1,1-diaminomethane

carbon dioxide

methylamine hydrochloride