1,2-diphenylpropan-1-one

Base Information

• Chemical Name: 1,2-diphenylpropan-1-one
• CAS No.: 2042-85-5
• Molecular Formula: C15H14 O
• Molecular Weight: 210.276
• Hs Code.: 2914399090
• Mol file: 2042-85-5.mol

Synonyms:Propiophenone,2-phenyl- (6CI,7CI,8CI); 1,2-Diphenyl-1-propanone; 1,2-Diphenylpropan-2-one;2-Phenyl-2-methylacetophenone; 2-Phenylpropiophenone; Hydratropophenone; NSC42897; Phenyl 1-phenylethyl ketone; a-Methylbenzyl phenyl ketone; a-Methyldeoxybenzoin; a-Methyldesoxybenzoin

Chemical Property of 1,2-diphenylpropan-1-one

Chemical Property:

• Vapor Pressure: 0.000264mmHg at 25°C
• Melting Point: 59.5-59.6 °C
• Boiling Point: 323.3°Cat760mmHg
• Flash Point: 137.1°C
• PSA: 17.07000
• Density: 1.057g/cm³
• LogP: 3.67300

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-diphenylpropan-1-one

There total 177 articles about 1,2-diphenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

chlorobenzene (108-90-7) + 1-phenyl-propan-1-one (93-55-0) → 1,2-diphenylpropan-1-one (2042-85-5)

Guidance literature:

With sodium t-butanolate; (SIPr)Pd(allyl)Cl; In tetrahydrofuran; at 70 ℃; for 1h; Further Variations:; Catalysts; Product distribution;

DOI:10.1021/ol026745m

Reference yield: 98.0%

1-phenyl-propan-1-one (93-55-0) → 1,2-diphenylpropan-1-one (2042-85-5)

Guidance literature:

bromobenzene; With sodium t-butanolate; palladium diacetate; tri-tert-butylphosphonium tetraphenylborate; In tetrahydrofuran; at 25 ℃; for 0.5h;

1-phenyl-propan-1-one; In tetrahydrofuran; at 25 ℃; for 17h; Product distribution / selectivity;

Reference yield: 97.0%

1,2-diphenylprop-2-en-1-one (4452-11-3) → 1,2-diphenylpropan-1-one (2042-85-5)

Guidance literature:

With hydrogen iodide; In water; chlorobenzene; at 110 ℃; for 8h;

upstream raw materials:

phenyl benzyl ketone

2,2-diphenylpropanal

1-phenylethyl cyanide

2-phenylpropanamide

Downstream raw materials:

α'-oxy-α-methyl-α'-ethyl-dibenzyl

erythro-1-amino-1,2-diphenylpropane

benzoic acid

1,1,2-triphenyl-1-propanol

Refernces

• 1、 Ueda, Yusuke,Iwai, Tomohiro,Sawamura, Masaya. "Nickel-Copper-Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes". . p. 9410 - 9414. Retrieved 2019.
• 2、 Vignolle, Joan,Gornitzka, Heinz,Donnadieu, Bruno,Bourissou, Didier,Bertrand, Guy. "Palladium-oxygen and palladium-arene interactions in complexes derived from biaryl aminocarbenes: Comparison with biaryl phosphanes". . p. 2271 - 2274. Retrieved 2008.
• 3、 Descotes,Sinou. "-". . p. 4083. Retrieved 1976.
• 4、 Halpern, Marc,Sasson, Yoel,Willner, Itamar,Rabinovitz, Mordecai. "HYDROXIDE ION INITIATED REACTIONS UNDER PHASE TRANSFER CATALYSIS CONDITIONS II. THE ROLES OF WATER AND QUAT". . p. 1719 - 1722. Retrieved 1981.
• 5、 Sivaguru,Solomon, Marissa R.,Saito, Hideaki,Poon, Thomas,Jockusch, Steffen,Adam, Waldemar,Inoue, Yoshihisa,Turro, Nicholas J.. "Conformationally controlled (entropy effects), stereoselective vibrational quenching of singlet oxygen in the oxidative cleavage of oxazolidinone-functionalized enecarbamates through solvent and temperature variations". . p. 6707 - 6717. Retrieved 2006.
• 6、 Matsumoto, Shoji,Marumoto, Hayato,Akazome, Motohiro,Otani, Yasuhiko,Kaiho, Tatsuo. "Chemoselective reduction of ?,￠-unsaturated carbonyl and carboxylic compounds by hydrogen iodide". . p. 590 - 599. Retrieved 2021/03/29.
• 7、 -. "LIGANDS FOR TRANSITION METAL CATALYSTS". Page/Page column 35-36. . Retrieved 2021/07/17.