CARPROPAMID

Base Information

• Chemical Name: CARPROPAMID
• CAS No.: 115252-91-0
• Molecular Formula: C₁₅H₁₈Cl₃NO
• Molecular Weight: 334.673
• Mol file: 115252-91-0.mol

Synonyms:CARPROPAMID;2,2-DICHLORO-N-[1-(4-CHLOROPHENYL)ETHYL]-1-ETHYL-3-METHYLCYCLOPROPANECARBOXAMIDE

Chemical Property of CARPROPAMID

Chemical Property:

• Storage Temp.: 0-6°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CARPROPAMID

There total 3 articles about CARPROPAMID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(trans)-2,2-dichloro-1-ethyl-3-methylcyclopropanecarbonyl chloride (113941-76-7) + p-chloro-(R,S)-1-phenylethylamine (35588-60-4) → carpropamid (104030-54-8,115252-91-0)

Guidance literature:

With 1-methyl-1H-imidazole; N,N,N,N,-tetramethylethylenediamine; potassium carbonate; In acetonitrile; at 0 - 5 ℃; for 1h;

DOI:10.1016/j.tet.2007.08.117

Reference yield: 57.0%

(1S,3R)-2,2-dichloro-1-ethyl-3-methylcyclopropanecarboxylic acid (127640-94-2) + (S)-1-(p-chlorophenyl)ethylamine (4187-56-8) → (1S,3R)-2,2-dichloro-N-[(S)-1-(4-chlorophenyl)ethyl]-1-ethyl-3-methylcyclopropanecarboxamide (104030-54-8,115252-91-0)

Guidance literature:

(1S,3R)-2,2-dichloro-1-ethyl-3-methylcyclopropanecarboxylic acid; With 1-methyl-1H-imidazole; p-toluenesulfonyl chloride; In acetonitrile; at 0 - 5 ℃; for 0.5h; Inert atmosphere;

(S)-1-(p-chlorophenyl)ethylamine; In acetonitrile; at 0 - 5 ℃; for 2h;

DOI:10.1039/b714614k

Reference yield:

→ carpropamid (104030-54-8,115252-91-0)

Guidance literature:

upstream raw materials:

(trans)-2,2-dichloro-1-ethyl-3-methylcyclopropanecarbonyl chloride

p-chloro-(R,S)-1-phenylethylamine

(1S,3R)-2,2-dichloro-1-ethyl-3-methylcyclopropanecarboxylic acid

(S)-1-(p-chlorophenyl)ethylamine

Refernces

• 1、 -. "Synergistic Active Compound Combinations Comprising Phenyltriazoles". . . Retrieved 2011/07/29.
• 2、 Nakatsuji, Hidefumi,Morimoto, Mami,Misaki, Tomonori,Tanabe, Yoo. "Mild, powerful, and robust methods for esterification, amide formation, and thioesterification between acid chlorides and alcohols, amines, thiols, respectively". . p. 12071 - 12080. Retrieved 2008/03/13.