Ethyl chloro((4-nitrophenyl)hydrazono)acetate

Base Information

• Chemical Name: Ethyl chloro((4-nitrophenyl)hydrazono)acetate
• CAS No.: 27143-13-1
• Molecular Formula: C10H10 Cl N3 O4
• Molecular Weight: 271.66
• Hs Code.: 2928000090
• Mol file: 27143-13-1.mol

Synonyms:Ethyl chloro((4-nitrophenyl)hydrazono)acetate;27143-13-1;Ethyl 2-chloro-2-(2-(4-nitrophenyl)hydrazono)acetate;ethyl (2Z)-2-chloro-2-[(4-nitrophenyl)hydrazinylidene]acetate;Acetic acid, chloro((4-nitrophenyl)hydrazono)-, ethyl ester;A911272;(E)-ethyl 2-chloro-2-(2-(4-nitrophenyl)hydrazono)acetate

Chemical Property of Ethyl chloro((4-nitrophenyl)hydrazono)acetate

Chemical Property:

• Vapor Pressure: 2.71E-06mmHg at 25°C
• Boiling Point: 390.2°Cat760mmHg
• Flash Point: 189.8°C
• PSA: 96.51000
• Density: 1.41g/cm³
• LogP: 2.71830
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 271.0359835
• Heavy Atom Count: 18
• Complexity: 335

Purity/Quality:

99.90% ^*data from raw suppliers

Ethyl2-chloro-2-(2-(4-nitrophenyl)hydrazono)acetate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(=NNC1=CC=C(C=C1)[N+](=O)[O-])Cl
• Isomeric SMILES: CCOC(=O)/C(=N/NC1=CC=C(C=C1)[N+](=O)[O-])/Cl

Technology Process of Ethyl chloro((4-nitrophenyl)hydrazono)acetate

There total 5 articles about Ethyl chloro((4-nitrophenyl)hydrazono)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) + ethyl 2-chloro-3-oxo-butyrate (609-15-4) → chloro-(4-nitro-phenylhydrazono)-acetic acid ethyl ester (27143-13-1)

Guidance literature:

With hydrogenchloride; sodium nitrite; Yield given. Multistep reaction; 1.) 5 deg C, 3 h;

Reference yield:

ethyl 2-((4-nitrophenyl)hydrazono)-3-oxobutanoate (18795-00-1,77083-78-4,77083-80-8) → chloro-(4-nitro-phenylhydrazono)-acetic acid ethyl ester (27143-13-1)

Guidance literature:

With chloroform; chlorine;

DOI:10.1039/jr9330001143

Reference yield:

diazoacetic acid ethyl ester (623-73-4) + 4-nitrobenzenediazonium chloride (100-05-0) → chloro-(4-nitro-phenylhydrazono)-acetic acid ethyl ester (27143-13-1)

Guidance literature:

upstream raw materials:

diazoacetic acid ethyl ester

methanol

4-nitrobenzenediazonium chloride

ethyl 2-((4-nitrophenyl)hydrazono)-3-oxobutanoate

Downstream raw materials:

Ethyl <(2,6-dimethylphenyl)amino><(4-nitrophenyl)hydrazono>acetate

Ethyl <(2,6-dimethylphenyl)amino><(4-nitrophenyl)hydrazono>acetate

amino-(4-nitro-phenylhydrazono)-acetic acid ethyl ester

4-ethoxy-1-(4-nitro-phenyl)-4-oxo-1,4-dihydro-4λ⁵-[1,2,4]diazaphosphinine-3-carboxylic acid ethyl ester

Refernces

• 1、 Shawali, Ahmad S.,Albar, Hassan A.. "Kinetics and mechanism of dehydrochlorination of N-aryl-C-ethoxycarbonylformohydrazidoyl chlorides". . p. 871 - 875. Retrieved 2007/10/02.