Lorcainide hydrochloride

Base Information Edit

Chemical Name:Lorcainide hydrochloride
CAS No.:58934-46-6
Molecular Formula:C22H27 Cl N2 O . Cl H
Molecular Weight:407.383
Hs Code.:
European Community (EC) Number:261-504-6
NSC Number:310411
UNII:1T1S98ONM1
DSSTox Substance ID:DTXSID00974434
Wikidata:Q27252850
NCI Thesaurus Code:C66034
ChEMBL ID:CHEMBL3085477
Mol file:58934-46-6.mol

Synonyms:4'-chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide;lorcainid;lorcainide;lorcainide monohydrochloride;R 15889;R15889;Ro 13-1042

Suppliers and Price of Lorcainide hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(4-CHLOROPHENYL)-2-PHENYL-N-(1-PROPAN-2-YL-3,4,5,6-TETRAHYDRO-2H-PYRIDIN-4-YL)ACETAMIDE CHLORIDE 95.00%
5MG
$ 500.72

Alfa Aesar
Lorcainide hydrochloride, 98%
10mg
$ 126.00

Total 6 raw suppliers

Chemical Property of Lorcainide hydrochloride Edit

Chemical Property:

Vapor Pressure:3.01E-10mmHg at 25°C
Melting Point:263°
Boiling Point:503°C at 760 mmHg
Flash Point:258°C
PSA：23.55000
LogP:5.52840
Storage Temp.:-20°C
Solubility.:Soluble in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:406.1578689
Heavy Atom Count:27
Complexity:433

Purity/Quality:

95-99% ^*data from raw suppliers

N-(4-CHLOROPHENYL)-2-PHENYL-N-(1-PROPAN-2-YL-3,4,5,6-TETRAHYDRO-2H-PYRIDIN-4-YL)ACETAMIDE CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)N1CCC(CC1)N(C2=CC=C(C=C2)Cl)C(=O)CC3=CC=CC=C3.Cl
Description Lorcainide hydrochloride (58934-46-6) is a voltage-gated Na+?channel blocker.1?Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation.2?Acts at the ouabain binding site of guinea pig cardiac Na+/K+?ATPase and inhibits the enzyme (IC50?= 34 μM).3
Uses Cardiac depressant (anti-arrhythmic).

Technology Process of Lorcainide hydrochloride

There total 1 articles about Lorcainide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: