(S)-4-Isobutylpyrrolidin-2-one

Base Information Edit

Chemical Name:(S)-4-Isobutylpyrrolidin-2-one
CAS No.:181289-23-6
Molecular Formula:C₈H₁₅NO
Molecular Weight:141.213
Hs Code.:
UNII:U92YAF3WPG
Nikkaji Number:J2.460.246J
Mol file:181289-23-6.mol

Synonyms:(S)-4-Isobutylpyrrolidin-2-one;181289-23-6;Pregabalin Lactam;(4S)-4-(2-methylpropyl)pyrrolidin-2-one;U92YAF3WPG;2-Pyrrolidinone, 4-(2-methylpropyl)-, (4S)-;pregabalin lactam impurity;(S)-Pregabalin Lactam;UNII-U92YAF3WPG;Pregabalin EP Impurity A;SCHEMBL268203;(s)-4-isobutyl-2-pyrrolidinone;GUGXRXLTTHFKHC-ZETCQYMHSA-N;(S)-4-(Isobutyl)pyrrolidin-2-one;MFCD19217624;BS-51712;CS-0096516;(4S)-4-(2-Methylpropyl)pyrrolidin-2-one ((S)-Pregabalin Lactam);(4S)-4-(2-methylpropyl)-2-Pyrrolidinone;2-Pyrrolidinone, 4-(2-methylpropyl)-, (S)-;Pregabalin EP impurity A

Suppliers and Price of (S)-4-Isobutylpyrrolidin-2-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-PregabalinLactam
500mg
$ 1165.00

Crysdot
(S)-4-Isobutylpyrrolidin-2-one 97%
5g
$ 762.00

Biosynth Carbosynth
(S)-4-(2-Methylpropyl)-2-pyrrolidinone
250 mg
$ 900.00

Biosynth Carbosynth
(S)-4-(2-Methylpropyl)-2-pyrrolidinone
100 mg
$ 450.00

Biosynth Carbosynth
(S)-4-(2-Methylpropyl)-2-pyrrolidinone
50 mg
$ 275.00

Biosynth Carbosynth
(S)-4-(2-Methylpropyl)-2-pyrrolidinone
25 mg
$ 180.00

Biosynth Carbosynth
(S)-4-(2-Methylpropyl)-2-pyrrolidinone
10 mg
$ 100.00

Total 14 raw suppliers

Chemical Property of (S)-4-Isobutylpyrrolidin-2-one Edit

Chemical Property:

Boiling Point:269.1±9.0 °C(Predicted)
Density:0.927±0.06 g/cm3(Predicted)
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:141.115364102
Heavy Atom Count:10
Complexity:131

Purity/Quality:

≥99.0% ^*data from raw suppliers

(S)-PregabalinLactam ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC1CC(=O)NC1
Isomeric SMILES:CC(C)C[C@H]1CC(=O)NC1
Uses (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.

Technology Process of (S)-4-Isobutylpyrrolidin-2-one

There total 52 articles about (S)-4-Isobutylpyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1101167-76-3
(4R)-4-(2-methylprop-1-enyl)pyrrolidin-2-one

: 1272663-99-6
(4S)-4-(2-methylprop-2-enyl)pyrrolidin-2-one

: 181289-23-6
(S)-4-isobutyl-pyrrolidin-2-one

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 12h;

Reference yield: 97.2%

: 181289-39-4
(S)-3-cyano-5-methylhexanoic acid ethyl ester

: 181289-23-6
(S)-4-isobutyl-pyrrolidin-2-one

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In ethanol; at 25 ℃; for 6h; under 37503.8 Torr; Reagent/catalyst; Temperature; Autoclave; Green chemistry;