Technology Process of safranal
There total 8 articles about safranal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 7 steps
1: 25 percent / NaOAc / acetic acid / 0.25 h / Ambient temperature
2: 65 percent / trifluoroacetic acid / CH2Cl2 / 0.25 h / 0 °C
3: 46.2 percent / 30percent H2O2 / methanol / 0.17 h / 0 °C
4: 93 percent / CCl4 / 16 h / Heating
5: 88.5 percent / thionyl chloride, pyridine / CH2Cl2 / 0.08 h / 0 °C
6: 90.6 percent / 1N KOH / methanol / 4 h / Ambient temperature
7: 27.4 percent / chromium trioxide-pyridine complex / 1 h / Ambient temperature
With
pyridine; potassium hydroxide; thionyl chloride; chromium trioxide pyridine; dihydrogen peroxide; sodium acetate;
trifluoroacetic acid;
In
methanol; tetrachloromethane; dichloromethane; acetic acid;
DOI:10.1248/cpb.29.105
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 72 percent / DIBAL-H / CH2Cl2
2: 68 percent / (COCl)2, DMSO, Et3N / tetrahydrofuran
With
oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(97)10038-7