Guanosine 5'-monophosphate disodium salt

Base Information

• Chemical Name: Guanosine 5'-monophosphate disodium salt
• CAS No.: 5550-12-9
• Molecular Formula: C10H12N5Na2O8P
• Molecular Weight: 407.187
• Hs Code.: 29349990
• Mol file: 5550-12-9.mol

Synonyms:5'-Guanylicacid, disodium salt (7CI,8CI,9CI);5'-GMP disodium salt;Disodium 5'-GMP;Disodium 5'-guanylate;Disodium GMP;Disodium guanosine 5'-monophosphate;Disodium guanosine 5'-phosphate;Disodium guanylate;E 627;GMP disodium salt;GMP sodium salt;Guanosine 5'-monophosphate disodium salt;Guanosine5'-phosphate disodium salt;Guanylic acid sodium salt;NSC 20265;Sodium5'-guanylate;Sodium GMP;Sodium guanosine 5'-monophosphate;Sodium guanylate;

Chemical Property of Guanosine 5'-monophosphate disodium salt

Chemical Property:

• Appearance/Colour: White crystalline powder
• Melting Point: 300 °C
• Boiling Point: 890.2oC at 760 mmHg
• Flash Point: 492.2oC
• PSA: 221.51000
• LogP: -1.11210
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble50mg/mL, clear, colorless to faintly yellow
• Water Solubility.: >50 g/L

Purity/Quality:

99.5% ^*data from raw suppliers

Guanylic Acid Sodium Salt (2'-,3'- mixture)from Yeast ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36/37/39-27-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Guanylate sodium is allowed flavoring agent allowed at home and abroad, often used together with MSG and sodium inosinate. When mixed for usage, it has multiplication effect on the taste. It can be used for all types of food and should be subject to appropriate use according to production needs. It is mainly used as condiments, being a new generation food by freshener. It is a kind of flavor agent with mushrooms flavor. It is often used in conjunction with sodium glutamate (adding amount is 1%~5%), there is a very significant increase in freshener effect. These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Flavor potentiator in foods.Sodium Guanylate is a salt replacement flavor enhancer. Food additive. Guanosine 5'-monophosphate disodium salt is a flavor enhancer which is a crystalline powder, colorless or white, and has characteristic taste. It is soluble in water, sparingly soluble in alcohol, and practically insoluble in ether. It is obtained by chemical synthesis. It is also termed sodium 5-guanylate and disodium guanosine-5-monophosphate.

Technology Process of Guanosine 5'-monophosphate disodium salt

There total 4 articles about Guanosine 5'-monophosphate disodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H14N6O10P2(2-)*2Na(1+) → guanosine 5'-monophosphate disodium (5550-12-9)

Guidance literature:

With water; zinc(II) cation; pH=5.5;

DOI:10.1038/nchem.2878

Reference yield:

guanosine-5'-phosphoro-(2-aminoimidazole) → 1H-imidazol-2-amine (7720-39-0) + guanosine 5'-monophosphate disodium (5550-12-9)

Guidance literature:

With trimethyl phosphite; water; sodium chloride; magnesium chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid; In water-d2; at 25 ℃; Kinetics;

DOI:10.1021/jacs.6b13148

Reference yield:

guanosine-5'-(2-methylimidazol-1-yl phosphate) (80242-42-8) → 2-methylimidazole (693-98-1) + guanosine 5'-monophosphate disodium (5550-12-9)

Guidance literature:

With trimethyl phosphite; water; sodium chloride; magnesium chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid; In water-d2; at 25 ℃; Kinetics;

DOI:10.1021/jacs.6b13148

upstream raw materials:

guanosine-5'-(2-methylimidazol-1-yl phosphate)

Refernces

• 1、 Gibard, Clémentine,Bhowmik, Subhendu,Karki, Megha,Kim, Eun-Kyong,Krishnamurthy, Ramanarayanan. "Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions". . p. 212 - 217. Retrieved 2018/02/06.