2,2-dichloro-N-phenylacetimidoyl chloride

Base Information

• Chemical Name: 2,2-dichloro-N-phenylacetimidoyl chloride
• CAS No.: 5512-78-7
• Molecular Formula: C₈H₆Cl₃N
• Molecular Weight: 222.501
• Mol file: 5512-78-7.mol

Synonyms:2,2-dichloro-N-phenylacetimidoyl chloride

Chemical Property of 2,2-dichloro-N-phenylacetimidoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-dichloro-N-phenylacetimidoyl chloride

There total 7 articles about 2,2-dichloro-N-phenylacetimidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

Acetanilid (103-84-4) → 2,2-dichloro-N-phenylacetimidoyl chloride (5512-78-7)

Guidance literature:

With thionyl chloride; In chloroform; at 90 ℃; for 3h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.5b01868

Reference yield: 35.0%

2,2,2-trichloro-N-phenylacetamide (2563-97-5) → 2,2-dichloro-N-phenylacetimidoyl chloride (5512-78-7)

Guidance literature:

With triphenylphosphine; In tetrachloromethane; dichloromethane; at 60 ℃; for 4h;

DOI:10.1080/07328301003597673

Reference yield:

N-phenyl-2,2-dichloroacetamide (2563-99-7) → 2,2-dichloro-N-phenylacetimidoyl chloride (5512-78-7)

Guidance literature:

With phosphorus pentachloride; benzene;

upstream raw materials:

N-phenyl-2,2-dichloroacetamide

Acetanilid

2,2,2-trichloro-N-phenylacetamide

N-chloroacetyl-aniline

Downstream raw materials:

N-phenyl-2,2-dichloroacetamide

N-phenyl-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl) dichloroacetimidate

N-Phenyl-2-chlor-acetimidoylchlorid

N,N-Diaethyl-N'-phenyl-2.2-dichlor-acetamid

Refernces

• 1、 Huchel, Uschi,Tiwari, Pallavi,Schmidt, Richard R.. "N-aryl-O-glycosyl haloacetimidates as glycosyl donors". experimental part. p. 61 - 75. Retrieved 2011/07/06.