(+)-Isoproterenol

Base Information

• Chemical Name: (+)-Isoproterenol
• CAS No.: 2964-04-7
• Molecular Formula: C11H17 N O3
• Molecular Weight: 211.261
• UNII: 70D2X5QMKK
• Nikkaji Number: J221.644B
• Wikidata: Q27166424
• ChEMBL ID: CHEMBL460574
• Mol file: 2964-04-7.mol

Synonyms:(+)-Isoproterenol;2964-04-7;(S)-4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol;(S)-Isoprenaline;Isoproterenol, (+)-;4-[(1s)-1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;70D2X5QMKK;d-Isoprenaline;d-Isoproterenol;d-N-Isopropylnorepinephrine;(+)-Isoprenaline;(S)-(+)-Isoproterenol;l-Isoproterenol;l-Isopropylnoradrenaline;ISOPROTERENOL, D-;(-)-alpha-(Isopropylaminomethyl)protocatechuyl alcohol;UNII-70D2X5QMKK;SCHEMBL4166;ISOPRENALINE, (S)-;CHEMBL460574;1,2-Benzenediol, 4-((1R)-1-hydroxy-2-((1-methylethyl)amino)ethyl)-;1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (S)-;BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)-, (+)-;Benzyl alcohol, 3,4-dihydroxy-alpha-((isopropylamino)methyl)-, (-)-;BDBM34652;CHEBI:94595;cid_6852409;BDBM50407518;PDSP1_000685;PDSP1_001115;PDSP2_000675;PDSP2_001099;NCGC00179436-01;NCGC00179436-02;LS-42867;AB00514694;EN300-6736848;Q27166424;4-[(1S)-1-hydroxy-2-[(propan-2-yl)amino]ethyl]benzene-1,2-diol;4-[(1S)-1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;tartaric acid;1,2-BENZENEDIOL, 4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)-;2,3-bis(oxidanyl)butanedioic acid;4-[(1S)-1-oxidanyl-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;2,3-dihydroxybutanedioic acid;4-[(1S)-1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol

Chemical Property of (+)-Isoproterenol

Chemical Property:

• Boiling Point: 417.5°Cat760mmHg
• Flash Point: 179.7°C
• Density: 1.199g/cm³
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 211.12084340
• Heavy Atom Count: 15
• Complexity: 187

Purity/Quality:

(S)-4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NCC(C1=CC(=C(C=C1)O)O)O
• Isomeric SMILES: CC(C)NC[C@H](C1=CC(=C(C=C1)O)O)O

Technology Process of (+)-Isoproterenol

There total 2 articles about (+)-Isoproterenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoproterenol (7683-59-2) → (S)-isoproterenol (2964-04-7) + isoprenaline (51-31-0)

Guidance literature:

With MCCD-HPS packed column; In hydrogenchloride; methanol; pH=8.6;

DOI:10.1021/ac0204909

Reference yield:

isoproterenol (7683-59-2) → (S)-isoproterenol (2964-04-7)

Guidance literature:

With L-Tartaric acid;

DOI:10.1007/BF00899647 DOI:10.1126/science.118.3061.249

Reference yield:

(S)-isoproterenol (2964-04-7) → Isoproterenone (121-28-8)

Guidance literature:

With (R)-epinephrine dehydrogenase; NADH; In aq. phosphate buffer; at 45 ℃; pH=6; Enzymatic reaction;

DOI:10.1016/j.procbio.2014.03.023

upstream raw materials:

isoproterenol

Downstream raw materials:

Isoproterenone

Refernces

• 1、 Gogaladze, Khatuna,Chankvetadze, Lali,Tsintsadze, Maia,Farkas, Tivadar,Chankvetadze, Bezhan. "Effect of basic and acidic additives on the separation of some basic drug enantiomers on polysaccharide-based chiral columns with acetonitrile as mobile phase". . p. 228 - 234. Retrieved 2015/03/18.