cinnamyl hexanoate

Base Information

• Chemical Name: cinnamyl hexanoate
• CAS No.: 78761-41-8
• Molecular Formula: C₁₅H₂₀O₂
• Molecular Weight: 232.323
• Mol file: 78761-41-8.mol

Synonyms:cinnamyl hexanoate

Chemical Property of cinnamyl hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of cinnamyl hexanoate

There total 3 articles about cinnamyl hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-Phenylprop-1-yne (673-32-5) + hexanoic acid (142-62-1) → cinnamyl hexanoate (78761-41-8)

Guidance literature:

With benzoic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 12h;

DOI:10.1139/v05-043

Reference yield: 47.0%

2-phenyl[1,3,2]dioxaborolane (4406-72-8) + allyl hexanoate (123-68-2) → cinnamyl hexanoate (78761-41-8)

Guidance literature:

With oxygen; copper(II) bis(trifluoromethanesulfonate); In N,N-dimethyl acetamide; at 40 ℃; for 72h; under 760.051 Torr; regioselective reaction;

DOI:10.1002/anie.201814493

Reference yield: 45.0%

2-Bromo-hexanoic acid (E)-3-phenyl-allyl ester (127951-07-9) → cinnamyl hexanoate (78761-41-8) + (3S,4R)-4-Benzyl-3-butyl-dihydro-furan-2-one (127951-09-1,127951-42-2) + (3S,4S)-4-Benzyl-3-butyl-dihydro-furan-2-one (127951-09-1,127951-42-2)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 1.5h; Yields of byproduct given; Heating;

DOI:10.1016/S0040-4039(00)99361-4

upstream raw materials:

2-Bromo-hexanoic acid (E)-3-phenyl-allyl ester

1-Phenylprop-1-yne

hexanoic acid

2-phenyl[1,3,2]dioxaborolane

Refernces

• 1、 Patil, Nitin T.,Pahadi, Nirmal K.,Yamamoto, Yoshinori. "Pd(O)-PhCOOH catalyzed addition of oxygen pronucleophiles to allenes and internal alkynes". . p. 569 - 573. Retrieved 2007/10/03.