2,5,7,10-Tetraoxaundecane

Base Information

• Chemical Name: 2,5,7,10-Tetraoxaundecane
• CAS No.: 4431-83-8
• Molecular Formula: C7H16 O4
• Molecular Weight: 164.202
• Hs Code.: 2901100000
• European Community (EC) Number: 224-631-8
• NSC Number: 5225
• UNII: 0AU083F9GJ
• DSSTox Substance ID: DTXSID20196131
• Nikkaji Number: J205.811A
• Wikidata: Q27236551
• Mol file: 4431-83-8.mol

Synonyms:BIS(2-METHOXYETHOXY)METHANE;4431-83-8;2,5,7,10-Tetraoxaundecane;Bis-methoxyethoxy methane;1-methoxy-2-(2-methoxyethoxymethoxy)ethane;UNII-0AU083F9GJ;0AU083F9GJ;NSC-5225;EINECS 224-631-8;Ethylene glycol monomethyl ether formal;EC 224-631-8;2,7,10-Tetraoxaundecane;NSC5225;bis-(2-Methoxyethoxy)methane;SCHEMBL1035786;DTXSID20196131;NSC 5225;MFCD00043945;AKOS006227976;BIS-METHOXYETHOXY METHANE [INCI];METHANE, BIS(2-METHOXYETHOXY)-;BS-23490;2,5,7,10-TETRAOXAUNDECANE (TOU);CS-0206384;FT-0623016;1-methoxy-2-(2-methoxy-ethoxy-methoxy)-ethane;F71231;FORMALDEHYDE BIS(2-METHOXYETHYL) ACETAL;1-methoxy-2-[(2-methoxyethoxy)-methoxy]-ethane;Q27236551

Chemical Property of 2,5,7,10-Tetraoxaundecane

Chemical Property:

• Vapor Pressure: 1.17mmHg at 25°C
• Refractive Index: 1.4140
• Boiling Point: 181.3°Cat760mmHg
• Flash Point: 77.5°C
• PSA: 36.92000
• Density: 0.968g/cm³
• LogP: 0.26990
• Water Solubility.: Fully miscible in water.
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 164.10485899
• Heavy Atom Count: 11
• Complexity: 59.5

Purity/Quality:

99.9% ^*data from raw suppliers

bis(2-Methoxyethoxy)methane ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCOCOCCOC
• Uses: bis(2-Methoxyethoxy)methane is a useful research chemical. bis(2-Methoxyethoxy)methane is used in preparation of tetraoxaundecane by aldol condensation of ethylene glycol monomethyl ether and formaldehyde.

Technology Process of 2,5,7,10-Tetraoxaundecane

There total 6 articles about 2,5,7,10-Tetraoxaundecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.4%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-methoxy-ethanol (109-86-4,95507-80-5) → bis(dimethoxyethyoxyl)methane (4431-83-8)

Guidance literature:

With Amberlyst₁₅ catalyst; In water; toluene; Reagent/catalyst; Solvent; Reflux;

Reference yield: 58.0%

diiodomethane (75-11-6) + 2-methoxy-ethanol (109-86-4,95507-80-5) → bis(dimethoxyethyoxyl)methane (4431-83-8)

Guidance literature:

tetrabutylammomium bromide; In benzene; at 75 ℃; for 5h; Product distribution; effect of temperature, various catalysts, various dihalomethanes, further alcohols;

Reference yield:

(2S,3S)-2,3-Bis(2-methoxyethoxymethoxy)-1,4-bis(4'-methylphenylsulfonyloxy)butane (216440-54-9) → bis(dimethoxyethyoxyl)methane (4431-83-8) + (4R,5R)-4,5-Bis-iodomethyl-[1,3]dioxolane

Guidance literature:

With sodium iodide; Multistep reaction. Title compound not separated from byproducts; 1.) acetone, reflux, overnight, 2.) 110 deg C, 0.05 mmHg;

upstream raw materials:

formaldehyd

2-methoxy-ethanol

diiodomethane

2-Methoxyethoxymethyl chloride

Downstream raw materials:

2-Methoxyethoxymethyl chloride

4-chlorotetrahydro-2H-pyran

Refernces

• 1、 Horley, Graeme A.,Ozturk, Turan,Turksoy, Figen,Wallis, John D.. "New substrates for the preparation of electroactive materials: The syntheses of chiral tetrathiafulvalene derivatives with hydroxy-functionalised butane-1,4-dithio bridges". . p. 3225 - 3231. Retrieved 2007/10/03.
• 2、 Nazaretyan,Torosyan,Babayan. "QUATERNARY AMMONIUM SALTS IN ALKYLATION REACTIONS (SYNTHESIS OF FORMALDEHYDE ACETALS).". . p. 2396 - 2400. Retrieved 2007/10/02.