(4-carboxyanilino)phenyl phenylsulfone

Base Information

• Chemical Name: (4-carboxyanilino)phenyl phenylsulfone
• CAS No.: 114194-15-9
• Molecular Formula: C₁₉H₁₅NO₃S
• Molecular Weight: 337.399
• Mol file: 114194-15-9.mol

Synonyms:(4-carboxyanilino)phenyl phenylsulfone

Chemical Property of (4-carboxyanilino)phenyl phenylsulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-carboxyanilino)phenyl phenylsulfone

There total 2 articles about (4-carboxyanilino)phenyl phenylsulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-Chlorophenyl phenyl sulfone (80-00-2,8012-45-1) + carbon monoxide (201230-82-2) + aniline (62-53-3) → (4-carboxyanilino)phenyl phenylsulfone (114194-15-9)

Guidance literature:

With bis(triphenylphosphine)palladium(II)-chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,2-bis-(diphenylphosphino)ethane; sodium iodide; In N,N-dimethyl acetamide; at 115 ℃; for 6h; various conditions: CO pressure (5-95 psig) and periods of time (4-32 h); further reagents: tri-o-tolylphosphine, tri-p-tolylphosphine, Ph₃P;

DOI:10.1021/jo960861j

Reference yield:

4-(phenylsulfonyl)benzoyl chloride (37991-83-6) + aniline (62-53-3) → (4-carboxyanilino)phenyl phenylsulfone (114194-15-9)

Guidance literature:

With benzene;

Reference yield:

(4-carboxyanilino)phenyl phenylsulfone (114194-15-9) → 4-(phenylsulfonyl)benzaldehyde (66-39-7)

Guidance literature:

With phosphorus pentachloride; 1,1,2,2-tetrachloroethane; at 140 ℃; Schuetteln einer Loesung des erhaltenen Chlorimins in Tetrachloraethan mit SnCl₂ in aether.HCl und Erwaermen des Reaktionsprodukts mit wss.HCl;

DOI:10.1039/jr9480000601

upstream raw materials:

4-(phenylsulfonyl)benzoyl chloride

aniline

4-Chlorophenyl phenyl sulfone

carbon monoxide

Downstream raw materials:

4-(phenylsulfonyl)benzaldehyde

Refernces