1,1-Dimethylhydrazine

Base Information

• Chemical Name: 1,1-Dimethylhydrazine
• CAS No.: 57-14-7
• Deprecated CAS: 88733-28-2
• Molecular Formula: C2H8N2
• Molecular Weight: 60.0989
• Hs Code.: 29280090
• European Community (EC) Number: 200-316-0
• ICSC Number: 0147
• NSC Number: 60517
• UN Number: 1163
• UNII: 4WPQ90N53J
• DSSTox Substance ID: DTXSID1020516
• Nikkaji Number: J1.917H
• Wikipedia: Unsymmetrical_dimethylhydrazine
• Wikidata: Q161296,Q83066366
• NCI Thesaurus Code: C1072
• Metabolomics Workbench ID: 53656
• Mol file: 57-14-7.mol

Synonyms:1,1-dimethyhydrazine;1,1-dimethylhydrazine;dimazine;dimazine dihydrochloride;dimazine hydrochloride;unsymmetrical dimethylhydrazine

Chemical Property of 1,1-Dimethylhydrazine

Chemical Property:

• Appearance/Colour: clear colorless liquid with an ammonia-like odor
• Melting Point: -57.2 °C
• Refractive Index: n20/D 1.4075(lit.)
• Boiling Point: 63.9 °C at 760 mmHg
• Flash Point: 1.1 °C
• PSA: 29.26000
• Density: 0.829 g/cm³
• LogP: 0.12200
• Water Solubility.: miscible
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 60.068748264
• Heavy Atom Count: 4
• Complexity: 11.5
• Transport DOT Label: Poison Inhalation Hazard Flammable Liquid Corrosive

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F, T, N
• Hazard Codes: F:Flammable;;
• Statements: R11:; R23/25:; R34:; R45:; R51/53:
• Safety Statements: S45:; S53:; S61:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Hydrazines
• Canonical SMILES: CN(C)N
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract. Inhalation of the vapour may cause lung oedema. The substance may cause effects on the central nervous system and liver.
• Effects of Long Term Exposure: The substance may have effects on the blood. This may result in anaemia. This substance is possibly carcinogenic to humans.

Technology Process of 1,1-Dimethylhydrazine

There total 46 articles about 1,1-Dimethylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(5S,5aS,8aS)-5-(N',N'-Dimethyl-hydrazino)-1,3,7-trimethyl-5,5a,8a,9-tetrahydro-1H-pyrrolo[3,4-g]quinazoline-2,4,6,8-tetraone (127510-73-0) → 1,3,7-Trimethyl-8a,9-dihydro-1H-pyrrolo[3,4-g]quinazoline-2,4,6,8-tetraone (127510-75-2) + N,N-Dimethylhydrazine (57-14-7)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield: 87.0%

(η5-C5Me4SiMe3)2Ti(Cl)(NHN(CH3)2) → N,N-Dimethylhydrazine (57-14-7)

Guidance literature:

With (η⁵-C₅Me₅)Rh(2-pyridylphenyl)H; hydrogen; In tetrahydrofuran; at 23 ℃; for 120h; under 3040.2 Torr; Reagent/catalyst; Catalytic behavior; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.6b08009

Reference yield: 78.0%

1-acetyl-2-methylhydrazine (29817-35-4) + platinum-on-carbon + isopropyl alcohol (67-63-0,8013-70-5) → N,N-Dimethylhydrazine (57-14-7)

Guidance literature:

With hydrogenchloride; formaldehyd; paraformaldehyde; platinum;

upstream raw materials:

tetrachloromethane

N,N-dimethylcarbamoyl azide

dimethylchloroamine

N-Nitrosodimethylamine

Downstream raw materials:

2-(N',N'-dimethyl-hydrazino)-1-phenyl-ethanol

1-(N',N'-dimethyl-hydrazino)-2-phenyl-propan-2-ol

pyridine-4-carboxylic acid

N-methylisonicotinamide

Refernces

• 1、 Peterson et al.. "-". . p. 1025. Retrieved 1969.
• 2、 Rowe,Audrieth. "-". . p. 563. Retrieved 1956.
• 3、 Pappas, Iraklis,Chirik, Paul J.. "Catalytic Proton Coupled Electron Transfer from Metal Hydrides to Titanocene Amides, Hydrazides and Imides: Determination of Thermodynamic Parameters Relevant to Nitrogen Fixation". . p. 13379 - 13389. Retrieved 2016.
• 4、 Stephan,Pasquet,Elkhatib,Goutelle,Delalu. "Ammonia-dimethylchloramine system: Kinetic approach in an aqueous medium and comparison with the mechanism involving liquid ammonia". . p. 340 - 351. Retrieved 2008/09/21.