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XYLAZINE HYDROCHLORIDE

Base Information Edit
  • Chemical Name:XYLAZINE HYDROCHLORIDE
  • CAS No.:23076-35-9
  • Molecular Formula:C12H16N2S.HCl
  • Molecular Weight:256.79
  • Hs Code.:29349990
  • European Community (EC) Number:245-417-0
  • UNII:NGC3S0882S
  • DSSTox Substance ID:DTXSID6040248
  • Wikidata:Q27284859
  • NCI Thesaurus Code:C75050
  • RXCUI:1366222
  • ChEMBL ID:CHEMBL1256022
  • Mol file:23076-35-9.mol
XYLAZINE HYDROCHLORIDE

Synonyms:4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride (9CI);4H-1,3-Thiazine,5,6-dihydro-2-(2,6-xylidino)-, monohydrochloride (8CI);5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride;BAY 1470hydrochloride;BAY-Va 1470;Celactal;Narcosyl;Rompun;Xylapan;Xylasol;Xylazine chloride;Xylazine hydrochloride;? Xylazine hydrochloride;

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Chemical Property of XYLAZINE HYDROCHLORIDE Edit
Chemical Property:
  • Vapor Pressure:0.00013mmHg at 25°C 
  • Melting Point:150-164?C (dec.) 
  • Boiling Point:334.2 °C at 760 mmHg 
  • Flash Point:155.9 °C 
  • PSA:49.69000 
  • Density:1.15g/cm3 
  • LogP:3.51880 
  • Storage Temp.:−20°C 
  • Solubility.:≥12.84 mg/mL in DMSO; ≥24.1 mg/mL in EtOH; ≥24.15 mg/mL in H2O 
  • Water Solubility.:Soluble in water 
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:2
  • Exact Mass:256.0800974
  • Heavy Atom Count:16
  • Complexity:230
Purity/Quality:
Safty Information:
  • Pictogram(s): Toxic
  • Hazard Codes:
  • Statements: 25-36/37/38 
  • Safety Statements: 26-36/37/39-45 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=C(C(=CC=C1)C)NC2=NCCCS2.Cl
  • Uses Xylazine hydrochloride is α2 class of adrenergic receptor agonist. As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression. It is a clonidine analoque. It acts on presynaptic and postsynaptic receptors of the central and peripheral nervous systems. It is used as a sedative, analgesic, muscle relaxant. It is also used to anesthetize rats/mice.
  • Clinical Use Xylazine Hydrochloride is an alpha-2 agonist with sedative, analgesic, and muscle relaxant properties. It is approved for use in dogs,cats,horses,deer,and elk. This agent causes vomiting in a large percentage of cats and in some dogs. Xylazine is antagonized by yohimbine. It produces effective analgesia in horses and is often used for treating the pain associated with colic and for sedation for minor procedures.It is also used in combination with ketamine for short-term feld procedures in horses,such as castration and suturing of extensive wounds,because this combination usually produces 15 to 20 minutes of recumbency. Extralabel use of xylazine for cesarean sections in cattle and other surgical procedures is common. Xylazine Hydrochloride is used in cats and dogs as a tranquilizer and in combination with other injectable agents for surgical procedures.