Technology Process of Azatadine
There total 9 articles about Azatadine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen; acetic acid;
In
ethanol;
at 60 ℃;
for 20h;
Solvent;
Temperature;
Reagent/catalyst;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrahydrofuran / -40 °C
2: H2SO4
With
sulfuric acid;
In
tetrahydrofuran;
DOI:10.1021/jm00105a069
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) n-BuLi / 1.) THF, -40 deg C
2: POCl3 / Heating
3: PPA / Heating
4: tetrahydrofuran / -40 °C
5: H2SO4
With
n-butyllithium; sulfuric acid; trichlorophosphate;
In
tetrahydrofuran;
DOI:10.1021/jm00105a069
