Methylmalonic acid

Base Information Edit

Chemical Name:Methylmalonic acid
CAS No.:516-05-2
Molecular Formula:C4H6O4
Molecular Weight:118.089
Hs Code.:29171900
European Community (EC) Number:208-219-5,693-939-6
NSC Number:25201
UNII:8LL8S712J7
DSSTox Substance ID:DTXSID00199549
Nikkaji Number:J6.302I
Wikipedia:Methylmalonic_acid
Wikidata:Q239598
Pharos Ligand ID:SHMAYA544DLA
Metabolomics Workbench ID:2030
ChEMBL ID:CHEMBL1232416
Mol file:516-05-2.mol

Synonyms:Acid, Methylmalonic;Methylmalonic Acid

Suppliers and Price of Methylmalonic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Methylmalonic Acid
1g
$ 418.00

TRC
Methylmalonic acid
5g
$ 60.00

TCI Chemical
Methylmalonic Acid >98.0%(T)
25g
$ 51.00

TCI Chemical
Methylmalonic Acid >98.0%(T)
100g
$ 136.00

Sigma-Aldrich
Methylmalonic acid 99%
25g
$ 132.00

Sigma-Aldrich
Methylmalonic acid 99%
5g
$ 56.20

Sigma-Aldrich
Methylmalonic acid solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 89.10

Sigma-Aldrich
Methylmalonic acid solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material
080-1ml
$ 86.30

Oakwood
Methylmalonic acid 98%
100g
$ 110.00

Oakwood
Methylmalonic acid 98%
5g
$ 10.00

Total 96 raw suppliers

Chemical Property of Methylmalonic acid Edit

Chemical Property:

Appearance/Colour:white crystals
Vapor Pressure:2.44E-05mmHg at 25°C
Melting Point:128-130 °C(lit.)
Refractive Index:1.4304 (estimate)
Boiling Point:334.4 °C at 760 mmHg
PKA:3.07, 5.76(at 25℃)
Flash Point:170.2 °C
PSA：74.60000
Density:1.402 g/cm³
LogP:-0.20830
Storage Temp.:?20°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:soluble
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:118.02660867
Heavy Atom Count:8
Complexity:103

Purity/Quality:: Methylmalonic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn,F
Statements: 36/37/38-36-20/21/22-11
Safety Statements: 26-36/37-16

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)O)C(=O)O
Uses 2-Methylpropanedioic acid binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status. Methylmalonic acid can be used as a substrate in:Esterification reactions by various catalysts.Synthesis of pyrimidinium betaines with formamidine.Synthesis of malonic acid half thioester (MAHT).
Biological Functions Methylmalonic acid is capable of diffusing out of cells in which it is being produced, so it may be detected in excess in the blood, CSF, and urine of patients with these various forms of the disease.

Technology Process of Methylmalonic acid

There total 42 articles about Methylmalonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%