N-(4-(dimethylamino)phenyl)-N-methylnitrous amide

Base Information

• Chemical Name: N-(4-(dimethylamino)phenyl)-N-methylnitrous amide
• CAS No.: 5369-30-2
• Molecular Formula: C₉H₁₃N₃O
• Molecular Weight: 179.222
• Mol file: 5369-30-2.mol

Synonyms:N-(4-(dimethylamino)phenyl)-N-methylnitrous amide

Chemical Property of N-(4-(dimethylamino)phenyl)-N-methylnitrous amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-(dimethylamino)phenyl)-N-methylnitrous amide

There total 5 articles about N-(4-(dimethylamino)phenyl)-N-methylnitrous amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N,N,N',N'-tetramethyl-para-phenylenediamine (100-22-1) → N-(4-(dimethylamino)phenyl)-N-methylnitrous amide (5369-30-2)

Guidance literature:

With sodium hydroxide; In ethanol; for 12h; Ambient temperature;

Reference yield: 47.0%

N,N,N',N'-tetramethyl-para-phenylenediamine (100-22-1) → N-(4-(dimethylamino)phenyl)-N-methylnitrous amide (5369-30-2) + N,N'-dimethyl-N,N'-dinitroso-p-phenylenediamine (6947-38-2)

Guidance literature:

With tert.-butylnitrite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In acetonitrile; at 20 ℃; for 60h;

DOI:10.1039/c7gc02775c

Reference yield:

N,N,N'-trimethyl-p-phenylenediamine (5369-34-6) → N-(4-(dimethylamino)phenyl)-N-methylnitrous amide (5369-30-2) + N'-nitroso-N,N,N'-trimethyl-3-nitro-p-phenylenediamine

Guidance literature:

With i-propyl nitrite; at 0 - 20 ℃; for 1h;

DOI:10.1021/ja9732744

upstream raw materials:

N,N,N',N'-tetramethyl-para-phenylenediamine

N,N,N'-trimethyl-p-phenylenediamine

acetic acid

Downstream raw materials:

N,N,N'-trimethyl-p-phenylenediamine

Refernces

• 1、 Loeppky, Richard N.,Singh, Sukhjeet P.,Elomari, Saleh,Hastings, Riley,Theiss, Thomas E.. "Evidence for radical cations in linked mechanisms of N,N-Dialkyl aromatic amine nitration and nitrosative dealkylation". . p. 5193 - 5202. Retrieved 2007/10/03.
• 2、 Dandia, Anshu,Sehgal, Varinder,Upreti, Mani. "SYNTHESIS OF DIHYDRO-2-(2-PHENYL-INDOLE-3-YL)-4-ARYL-1,5-BENZOTHIAZEPINES". . p. 93 - 99. Retrieved 2007/10/03.