Diisobutyl Phosphite

Base Information

• Chemical Name: Diisobutyl Phosphite
• CAS No.: 1189-24-8
• Molecular Formula: C8H19 O3 P
• Molecular Weight: 194.211
• Hs Code.: 2920901900
• European Community (EC) Number: 677-191-8
• Nikkaji Number: J536.546E
• Mol file: 1189-24-8.mol

Synonyms:Diisobutyl Phosphite;Phosphonic acid,bis(2-methylpropyl) ester;diisobutyl hydrogen phosphite;SCHEMBL269434;AKOS037645123;bis(2-methylpropyl) hydrogen phosphite;AS-57331

Chemical Property of Diisobutyl Phosphite

Chemical Property:

• Vapor Pressure: 0.073mmHg at 25°C
• Refractive Index: 1.4180-1.4220
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 52.28000
• Density: g/cm³
• LogP: 2.55080
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 194.10718146
• Heavy Atom Count: 12
• Complexity: 94.5

Purity/Quality:

99% ^*data from raw suppliers

Diisobutyl Phosphite ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)COP(O)OCC(C)C

Technology Process of Diisobutyl Phosphite

There total 11 articles about Diisobutyl Phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-methyl-propan-1-ol (78-83-1) → diisobutyl phosphite (1189-24-8) + phosphonic acid monoisobutyl ester (44744-68-5)

Guidance literature:

In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/op049958v

Reference yield: 95.0%

2-methyl-propan-1-ol (78-83-1) → diisobutyl phosphite (1189-24-8)

Guidance literature:

With pyridine; phosphorus trichloride; In diethyl ether; at 0 - 20 ℃;

DOI:10.1021/jo200522w

Reference yield: 86.0%

2-methyl-propan-1-ol (78-83-1) + Dimethyl phosphite (868-85-9) → diisobutyl phosphite (1189-24-8)

Guidance literature:

at 175 ℃; for 0.5h; under 12751.3 Torr; Microwave irradiation; Flow reactor;

DOI:10.3390/molecules23071618

upstream raw materials:

triisobutyl phosphite

2-methyl-propan-1-ol

phosphonic acid diethyl ester

propylamine

Downstream raw materials:

triisobutyl phosphite

phosphorochloridic acid diisobutyl ester

(α-hydroxy-3-nitro-benzyl)-phosphonic acid diisobutyl ester

Diisobutyl (2-pyridylamino)(4-fluorophenyl)methyl phosphonate

Refernces

• 1、 Da Matta, Carolina Barbosa Brito,De Queiroz, Aline Cavalcanti,Santos, Mariana Silva,Alexandre-Moreira, Magna Suzana,Gon?alves, Vinicius Tomaz,Del Cistia, Catarina De Nigris,Sant'Anna, Carlos Mauricio R.,DaCosta, Jo?o Batista N.. "Novel dialkylphosphorylhydrazones: Synthesis, leishmanicidal evaluation and theoretical investigation of the proposed mechanism of action". . p. 1 - 12. Retrieved 2015.
• 2、 Chandrasekar, Aditi,Brahmmananda Rao,Sundararajan, Mahesh,Ghanty, Tapan K.,Sivaraman. "Remarkable structural effects on the complexation of actinides with H-phosphonates: A combined experimental and quantum chemical study". supporting information. p. 3841 - 3850. Retrieved 2018/03/21.