l-3-Hydroxy-N-methylmorphinan bitartrate

Base Information Edit

Chemical Name:l-3-Hydroxy-N-methylmorphinan bitartrate
CAS No.:125-72-4
Molecular Formula:C17H23NO•C4H6O6
Molecular Weight:407.464
Hs Code.:
European Community (EC) Number:204-753-8
NSC Number:91012
Mol file:125-72-4.mol

Synonyms:l-3-Hydroxy-N-methylmorphinan bitartrate;Lemoran;Levorphan tartrate;125-72-4;Levorphanol bitartrate;D-(-)-Levorphanol tartrate;Levorphanol tartrate (in methanol as a free base);2,3-dihydroxybutanedioic acid;17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol;l-3-Hydroxy-N-methylmorphinan tartrate;Ro 1-5431/7;NSC-91012;Levorphanol, tartrate;Levo-Dromoran tartrate;DEXTRORPHAND-TARTRATE;NSC91012;Morphinan-3-ol, tartrate (1:1) (salt);FT-0670780;Morphinan-3-ol, tartrate (1:1) (salt), (-)-;Morphinan-6-ol, tartrate (1:1) (salt), stereoisomer;Morphinan-3-ol, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt);WLN: T6 G666/FQ 2AF Q FX ONT & TTJ IQ O-L & 622 QVYQYQVQ & 621

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of l-3-Hydroxy-N-methylmorphinan bitartrate Edit

Chemical Property:

Vapor Pressure:1.19E-17mmHg at 25°C
Boiling Point:759°Cat760mmHg
Flash Point:412.8°C
PSA：138.53000
Density:g/cm³
LogP:0.89570
Storage Temp.:-20°C
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:407.19440226
Heavy Atom Count:29
Complexity:491

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O.C(C(C(=O)O)O)(C(=O)O)O
Uses Orally active synthetic morphine analog. Analgesic (narcotic). Controlled substance.
Clinical Use Levorphanol is a potent μ agonist (approximately sixfold greater than morphine), and its uses, side effects, and physical dependence liability are like those of oxymorphone or hydromorphone. Levorphanol is available in oral, subcutaneous, and intravenous dosage forms. The oral dose of levorphanol is approximately twice the parenteral dose. This drug is unique among the μ agonists in that its analgesic duration of action is 4 to 6 hours, whereas its clearance half-life is 11.4 hours. Thus, effective analgesic doses of this agent can lead to a buildup of the drug in the body and result in excessive sedation.

Technology Process of l-3-Hydroxy-N-methylmorphinan bitartrate

There total 1 articles about l-3-Hydroxy-N-methylmorphinan bitartrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87-69-4,138508-61-9
L-Tartaric acid

: 77-07-6,125-73-5,297-90-5,2616-02-6,59684-82-1
Levorphanol

: 125-72-4,5497-47-2
levorphanol tartrate

Guidance literature:: L-Tartaric acid; Levorphanol; In water; isopropyl alcohol; at 40 - 75 ℃; for 0.75 - 1.25h;

With ammonia; In chloroform; water; isopropyl alcohol; at 20 - 30 ℃; for 0.25h;