Alpidem

Base Information

• Chemical Name: Alpidem
• CAS No.: 82626-01-5
• Molecular Formula: C21H23Cl2N3O
• Molecular Weight: 404.33
• European Community (EC) Number: 689-420-9
• UNII: I93SC245QZ
• DSSTox Substance ID: DTXSID8049046
• Nikkaji Number: J33.130I
• Wikipedia: Alpidem
• Wikidata: Q4735440
• NCI Thesaurus Code: C80669
• Pharos Ligand ID: 7DNR6XX8JGW2
• ChEMBL ID: CHEMBL54349
• Mol file: 82626-01-5.mol

Synonyms:alpidem;S-800342;SL 80-0342

Chemical Property of Alpidem

Chemical Property:

• Appearance/Colour: white to off-white solid
• Melting Point: 136-138 °C
• Refractive Index: 1.606
• PKA: 4.74±0.50(Predicted)
• PSA: 37.61000
• Density: 1.24 g/cm³
• LogP: 5.49920
• Storage Temp.: Refrigerator
• Solubility.: DMSO: ≥10mg/mL
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 403.1218178
• Heavy Atom Count: 27
• Complexity: 478

Purity/Quality:

98%Min ^*data from raw suppliers

Alpidem ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCN(CCC)C(=O)CC1=C(N=C2N1C=C(C=C2)Cl)C3=CC=C(C=C3)Cl
• Description: Alpidem is an imidazopyridine antianxiety agent with anticonvulsant properties. It is claimed to be the first non-benzodiazepine anxiolytic to show selectivity for the omega-1 modulatory site of the GABA, receptors. Alpidem is reported to be superior to buspirone and similar to the benzodiazepines, but is significantly better tolerated with lower abuse potential.
• Uses: A peripheral benzodiazepine GABAA receptor ligand, a new anxiolytic