Exenatide acetate

Base Information

• Chemical Name: Exenatide acetate
• CAS No.: 141732-76-5
• Molecular Formula: C184H282N50O60S.C2H4O2
• Molecular Weight: 4262.67
• Mol file: 141732-76-5.mol

Synonyms:Exendin4;UNII-9P1872D4OL;Extendin-4;

Chemical Property of Exenatide acetate

Chemical Property:

• PSA: 1812.35000
• LogP: -2.07850
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Acetonitrile (Slightly), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

ExenatideAcetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II. Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.
• Clinical Use: 39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.
• Drug interactions: Potentially hazardous interactions with other drugs Anticoagulants: possibly enhances anticoagulant effect of warfarin. Other nephrotoxins: avoid concomitant use.