Hydrogen sulfate;(4-hydroxyphenyl)-methylazanium

Base Information

• Chemical Name: Hydrogen sulfate;(4-hydroxyphenyl)-methylazanium
• CAS No.: 55-55-0
• Molecular Formula: 2(C7H9NO)^.H2SO4
• Molecular Weight: 344.389
• Hs Code.: 29222900
• Mol file: 55-55-0.mol

Synonyms:hydrogen sulfate;(4-hydroxyphenyl)-methylazanium;AKOS024390875;sulfuric acid compound with 4-(methylamino)phenol (1:1)

Chemical Property of Hydrogen sulfate;(4-hydroxyphenyl)-methylazanium

Chemical Property:

• Appearance/Colour: white crystalline powder
• Melting Point: 260 °C
• Refractive Index: 1.6510 (estimate)
• Boiling Point: 262.7 °C at 760 mmHg
• Flash Point: 148.6 °C
• PSA: 115.24000
• Density: 1.577
• LogP: 1.93490
• Storage Temp.: −20°C
• Sensitive.: Air Sensitive
• Solubility.: H2O: 50 mg/mL, clear
• Water Solubility.: 50 g/L (20 ºC)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 221.03579362
• Heavy Atom Count: 14
• Complexity: 153

Purity/Quality:

99% ^*data from raw suppliers

4-Methylaminophenol Sulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, N
• Hazard Codes: Xn,N
• Statements: 22-43-48/22-50/53
• Safety Statements: 36/37-46-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[NH2+]C1=CC=C(C=C1)O.OS(=O)(=O)[O-]
• Description: Metol is contained in black-and-white film developers and caused contact dermatitis in photographers.
• Uses: Photographic developer; dyeing furs. Metol is a black-and-white photographic developer; dyeing furs; as pigment in hair dyes. 4-(Methylamino)phenol sulfate is a photographic developer used in black and white photography. It is also used as tone developers in developing agents. Further, it is used in oxidative hair dye formulations. 4-methylaminophenol sulfate is used as a photographic developer and fur dye.

Technology Process of Hydrogen sulfate;(4-hydroxyphenyl)-methylazanium

There total 2 articles about Hydrogen sulfate;(4-hydroxyphenyl)-methylazanium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic acid-(4-benzylidenamino-phenyl ester) (13031-47-5) + dimethyl sulfate (77-78-1) → 4-(methylamino)phenol sulphate (55-55-0,1936-57-8)

Guidance literature:

at 135 ℃; Zersetzen mit Wasser und Kochen mit konz.Salzsaeure;

Reference yield:

p-aminophenol hydrochloride (51-78-5) + dimethyl sulfate (77-78-1) → 4-(methylamino)phenol sulphate (55-55-0,1936-57-8)

Guidance literature:

Yield given. Multistep reaction;

Reference yield: 97.0%

4-(methylamino)phenol sulphate (55-55-0,1936-57-8) + tert-butyldimethylsilyl chloride (18162-48-6) → 4-[(tert-butyldimethylsilyl)oxy]-N-methylaniline (90446-71-2)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/j.tetlet.2005.10.005

upstream raw materials:

acetic acid-(4-benzylidenamino-phenyl ester)

dimethyl sulfate

p-aminophenol hydrochloride

Downstream raw materials:

4-[(7-chloro-quinolin-4-yl)-methyl-amino]-phenol

6-nitro-benzo[1,3]dioxole-5-carboxylic acid-(4-hydroxy-N-methyl-anilide)

2-(4-hydroxy-N-methyl-anilino)-ethanol

N-methyl-(4-acetamido)phenol

Refernces