2-Acetyl-3-ethylpyrazine

Base Information

• Chemical Name: 2-Acetyl-3-ethylpyrazine
• CAS No.: 32974-92-8
• Molecular Formula: C8H10N2O
• Molecular Weight: 150.18
• Hs Code.: 29339900
• European Community (EC) Number: 251-316-2
• UNII: AQ03N14XTL
• DSSTox Substance ID: DTXSID3067736
• Nikkaji Number: J319.481G
• Wikidata: Q27274053
• Metabolomics Workbench ID: 43822
• Mol file: 32974-92-8.mol

Synonyms:2-Acetyl-3-ethylpyrazine;32974-92-8;1-(3-ethylpyrazin-2-yl)ethanone;1-(3-Ethylpyrazinyl)ethan-1-one;Ethanone, 1-(3-ethylpyrazinyl)-;2-Acetyl-3-ethyl-1,4-diazine;2-acetyl-3-ethyl pyrazine;1-(3-ethylpyrazin-2-yl)ethan-1-one;1-(3-Ethylpyrazinyl)ethanone;FEMA No. 3250;Ethanone, 1-(ethylpyrazinyl)-;3-Ethyl-2-acetylpyrazine;MFCD00038028;UNII-AQ03N14XTL;Ethanone, 1-(3-ethyl-2-pyrazinyl)-;2-Ethyl-3-acetyl pyrazine;AQ03N14XTL;Pyrazine, 2-acetyl-3-ethyl;1-(3-Ethyl-2-pyrazinyl)ethanone;EINECS 251-316-2;2-ACETYL ETHYLPYRAZINE;SCHEMBL1532459;1-(3-Ethylpyrazinyl)-Ethanone;DTXSID3067736;FEMA 3250;CHEBI:173401;1-(3-Ethyl-2-pyrazinyl)-Ethanone;1-(3-Ethylpyrazinyl)ethanone, 9CI;AC8556;1-(3-Ethyl-pyrazin-2-yl)-ethanone;Etanona, 1-(3-etil-2-pirazinil)-;2-Acetyl-3-ethylpyrazine, 98%, FG;AKOS005256376;FS-1047;HY-W039157;2-ACETYL-3-ETHYLPYRAZINE [FHFI];SY027477;CS-0096817;FT-0610950;A821538;Q-100406;Q27274053

Chemical Property of 2-Acetyl-3-ethylpyrazine

Chemical Property:

• Vapor Pressure: 0.0258mmHg at 25°C
• Refractive Index: n20/D 1.515(lit.)
• Boiling Point: 247.3 °C at 760 mmHg
• PKA: 0.56±0.10(Predicted)
• Flash Point: 86.7 °C
• PSA: 42.85000
• Density: 1.07 g/cm³
• LogP: 1.24160
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 150.079312947
• Heavy Atom Count: 11
• Complexity: 147

Purity/Quality:

99% ^*data from raw suppliers

2-Acetyl-3-ethylpyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=NC=CN=C1C(=O)C
• Description: 2-Acetyl-3-ethylpyrazine has a nutty, popcorn, potato chip, meaty odor.

Technology Process of 2-Acetyl-3-ethylpyrazine

There total 1 articles about 2-Acetyl-3-ethylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-ethyl-3-acetyl pyrazine (32974-92-8)

Guidance literature:

rohes /BRN= 638017/ (2b), 2-Nitropropan, NaOEt;

DOI:10.1021/jo00968a047

Reference yield: 94.0%

4-bromo-benzaldehyde (1122-91-4) + 2-ethyl-3-acetyl pyrazine (32974-92-8) → (E)-3-(4-bromophenyl)-1-(3-ethylpyrazin-2-yl)prop-2-en-1-one (1433999-50-8)

Guidance literature:

With potassium carbonate; In neat (no solvent); at 70 ℃; for 0.108333h; under 15001.5 Torr; Microwave irradiation;

DOI:10.1039/c3nj00308f

Reference yield: 92.0%

4-fluorobenzaldehyde (459-57-4) + 2-ethyl-3-acetyl pyrazine (32974-92-8) → (E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one (1433999-48-4)

Guidance literature:

With potassium carbonate; In neat (no solvent); at 70 ℃; for 0.125h; under 15001.5 Torr; Microwave irradiation;

DOI:10.1039/c3nj00308f

Downstream raw materials:

2-(N-t-butylbenzyl)aminoethyl-2-(3-ethyl)-pyrazylketone

2-(N-hydroxyethylbenzyl)aminoethyl-2-(3-ethyl)-pyrazylketone

2-(N-isopropylbenzyl)aminoethyl-2-(3-ethyl)-pyrazylketone

(E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one