2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene

Base Information

• Chemical Name: 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene
• CAS No.: 7128-64-5
• Deprecated CAS: 59249-63-7,12224-40-7,144470-46-2,61229-63-8,864446-12-8,1197996-34-1,1430334-83-0,2369674-07-5,1197996-34-1,144470-46-2,61229-63-8,864446-12-8
• Molecular Formula: C26H26N2O2S
• Molecular Weight: 430.571
• Hs Code.: Oral rat LD50: >10 gm/kg
• European Community (EC) Number: 230-426-4
• NSC Number: 158163
• UNII: W7UR9129GP
• DSSTox Substance ID: DTXSID1048205
• Nikkaji Number: J1.845G
• Wikidata: Q26840908
• Metabolomics Workbench ID: 163618
• Mol file: 7128-64-5.mol

Synonyms:4,4'-bis(2-di(2-hydroxyethyl)amino-4-(3-sulphophenylamino)-1,3,5-triazine-6-ylamino)stilbene-2,2'-disulphonic acid;Uvitex 2B

Chemical Property of 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene

Chemical Property:

• Appearance/Colour: light yellow-green crystals
• Vapor Pressure: 7.83E-11mmHg at 25°C
• Melting Point: 199-201 °C(lit.)
• Refractive Index: 1.617
• Boiling Point: 531.2 °C at 760 mmHg
• PKA: 3.03±0.10(Predicted)
• Flash Point: 275.1 °C
• PSA: 80.30000
• Density: 1.185 g/cm³
• LogP: 7.95950
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: toluene: soluble50mg/mL
• Water Solubility.: Soluble in acetone and toluene. Insoluble in water.
• XLogP3: 8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 430.17149925
• Heavy Atom Count: 31
• Complexity: 590

Purity/Quality:

98.5%min ^*data from raw suppliers

2,5-Bis(5-tert-butylbenzooxazol-2-yl)thiophene ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Dyes -> Other Dyes
• Canonical SMILES: CC(C)(C)C1=CC2=C(C=C1)OC(=N2)C3=CC=C(S3)C4=NC5=C(O4)C=CC(=C5)C(C)(C)C
• Description: 2,5-Bis (5-tert-butyl-2-benzoxazolyl) thiophene (also known as fluorescent brightener 184)1 is used as an optical brightener, which converts UV light into visible light. It is also used as a fluorescent brightener for thermoplastic resins of polyvinyl chloride, acrylic resin, polyester fiber, thermoplastic plastic, ABS, cellulose acetate fiber, paint, coating and printing ink. It is also useful in detecting the presence of thin-film electrical contact lubricants2-4.
• Uses: Optical brightener additive in polymers, fibers, films, inks, laquers, and paints. In liquid scintillators. 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene is used as an optical brightener which converts UV light into visible light. It is also used as a fluorescent brightener for thermoplastic resins of polyvinyl chloride, acrylic resin, polyester fiber, paint, coating and printing ink. It is also useful in detecting the presence of thin-film electrical contact lubricants.

Technology Process of 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene

There total 6 articles about 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

Thiophene-2,5-dicarboxylic acid (4282-31-9) + 2-amino-4-tert-butylphenol (1199-46-8) → Uvitex OB (7128-64-5,12224-40-7)

Guidance literature:

With boric acid; In toluene; at 170 - 240 ℃; Solvent; Temperature; Inert atmosphere;

Reference yield: 75.0%

2,5-thiophenedicarboxaldehyde (932-95-6) + 4-tert-Butylcatechol (98-29-3) → Uvitex OB (7128-64-5,12224-40-7)

Guidance literature:

With sodium periodate; ammonium acetate; In ethyl acetate; at 100 ℃; for 8h; Schlenk technique; Inert atmosphere;

DOI:10.1002/adsc.202100249

Reference yield:

Thiophene-2,5-dicarboxylic acid bis-[(5-tert-butyl-2-hydroxy-phenyl)-amide] → Uvitex OB (7128-64-5,12224-40-7)

Guidance literature:

at 200 ℃; for 3h; Yield given;

DOI:10.1002/hlca.19800630212

upstream raw materials:

thiophene-2,5-dicarbonyl dichloride

Thiophene-2,5-dicarboxylic acid

2-amino-4-tert-butylphenol

2,5-thiophenedicarboxaldehyde

Refernces

• 1、 Dong, Jianyu,Geng, Furong,Su, Lebin,Wu, Shaofeng,Yin, Shuang-Feng,Zhou, Dan,Zhou, Yongbo. "Metal-Free Oxidative Condensation of Catechols, Aldehydes and NH4OAc towards Benzoxazoles". supporting information. p. 3607 - 3614. Retrieved 2021/07/28.
• 2、 -. "Process for the preparation of bis-benzazolyl compounds". Page/Page column 3. . Retrieved 2008/06/13.