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1,3-Thiazol-2-ylmethanol

Base Information Edit
  • Chemical Name:1,3-Thiazol-2-ylmethanol
  • CAS No.:14542-12-2
  • Molecular Formula:C4H5NOS
  • Molecular Weight:115.156
  • Hs Code.:2934100090
  • European Community (EC) Number:696-096-2
  • DSSTox Substance ID:DTXSID80383585
  • Nikkaji Number:J687.521A
  • Wikidata:Q72508340
  • Mol file:14542-12-2.mol
1,3-Thiazol-2-ylmethanol

Synonyms:1,3-Thiazol-2-ylmethanol;14542-12-2;thiazol-2-ylmethanol;2-Thiazolemethanol;Thiazol-2-yl-methanol;2-Hydroxymethylthiazole;2-(Hydroxymethyl)thiazole;thiazole-2-methanol;(1,3-Thiazol-2-yl)methanol;(thiazol-2-yl)methanol;MFCD06200855;2-(Hydroxymethyl)-1,3-thiazole;2-thiazolylmethanol;hydroxymethylthiazole;2-(Hydroxylmethyl)thiazole;SCHEMBL167744;2-HYDROXYMETHYL-THIAZOLE;DTXSID80383585;JNHDLNXNYPLBMJ-UHFFFAOYSA-N;STR07382;BBL100903;GEO-02297;STL554697;AKOS005255281;1,3-thiazol-2-ylmethanol, AldrichCPR;AB89861;PS-3716;AC-26524;AM803222;SY017208;CS-0028735;FT-0647582;H1476;EN300-51258;A19584;A808365;W-200117;Z57161013;F1160-0003

Suppliers and Price of 1,3-Thiazol-2-ylmethanol
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • 1,3-Thiazol-2-ylmethanol
  • 500mg
  • $ 333.00
  • Usbiological
  • 1,3-Thiazol-2-ylmethanol
  • 1g
  • $ 305.00
  • TRC
  • 1,3-Thiazol-2-ylmethanol
  • 5g
  • $ 175.00
  • TCI Chemical
  • 2-(Hydroxymethyl)thiazole >98.0%(GC)
  • 1g
  • $ 125.00
  • SynQuest Laboratories
  • 2-(Hydroxymethyl)-1,3-thiazole 97.0%
  • 250 mg
  • $ 39.00
  • Matrix Scientific
  • 2-(Hydroxymethyl)thiazole 96%
  • 1g
  • $ 88.00
  • Matrix Scientific
  • 2-(Hydroxymethyl)thiazole 96%
  • 5g
  • $ 255.00
  • JR MediChem
  • 2-Hydroxymethylthiazole 97%
  • 25g
  • $ 398.00
  • Frontier Specialty Chemicals
  • 2-(Hydroxymethyl)thiazole 95%
  • 1g
  • $ 25.00
  • Frontier Specialty Chemicals
  • 2-(Hydroxymethyl)thiazole 95%
  • 5g
  • $ 90.00
Total 65 raw suppliers
Chemical Property of 1,3-Thiazol-2-ylmethanol Edit
Chemical Property:
  • Appearance/Colour:white to light yellow crystal powder 
  • Vapor Pressure:0.105mmHg at 25°C 
  • Melting Point:62-64.5 °C(lit.) 
  • Refractive Index:1.594 
  • Boiling Point:212.077 °C at 760 mmHg 
  • PKA:12.87±0.10(Predicted) 
  • Flash Point:82.061 °C 
  • PSA:61.36000 
  • Density:1.34 g/cm3 
  • LogP:0.63540 
  • Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C 
  • XLogP3:0.1
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:115.00918496
  • Heavy Atom Count:7
  • Complexity:59.7
Purity/Quality:

98%,99%, *data from raw suppliers

1,3-Thiazol-2-ylmethanol *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn 
  • Hazard Codes:Xn 
  • Statements: 20/21/22-36/37/38 
  • Safety Statements: 22-26-36/37/39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CSC(=N1)CO
  • Uses 1,3-Thiazol-2-ylmethanol is a reagent used in the synthesis of quinazoline analogs which is an anti-proliferative activities and EGFR inhibitory potency.
Technology Process of 1,3-Thiazol-2-ylmethanol

There total 12 articles about 1,3-Thiazol-2-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With methanol; sodium tetrahydroborate; at 0 - 30 ℃; for 1h;
DOI:10.1002/cjoc.201400271
Guidance literature:
With sodium tetrahydroborate; In methanol; for 2h; Ambient temperature;
DOI:10.1016/S0040-4020(01)90345-X
Guidance literature:
With sulfuric acid; for 2.5h; Heating;
DOI:10.1016/S0040-4020(01)87090-3
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