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(R)-1-Boc-3-hydroxypiperidine

Base Information Edit
  • Chemical Name:(R)-1-Boc-3-hydroxypiperidine
  • CAS No.:143900-43-0
  • Molecular Formula:C10H19NO3
  • Molecular Weight:201.266
  • Hs Code.:29333990
  • European Community (EC) Number:626-867-0
  • DSSTox Substance ID:DTXSID60363880
  • Nikkaji Number:J2.623.316J
  • Wikidata:Q72449622
  • Mol file:143900-43-0.mol
(R)-1-Boc-3-hydroxypiperidine

Synonyms:(R)-1-Boc-3-hydroxypiperidine;143900-43-0;(R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate;tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate;(r)-n-boc-3-hydroxypiperidine;(R)-1-N-Boc-3-hydroxypiperidine;(R)-1-Boc-3-piperidinol;1-Piperidinecarboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester, (3R)-;MFCD04115306;(R)-1-(tert-butoxycarbonyl)-3-hydroxypiperidine;(r)-1-boc-3-hydroxylpiperidine;(r)-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester;(3R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine;SCHEMBL215146;R-1-BOC-3-Hydroxy-piperidine;N-BOC-3(R)-hydroxy-piperidine;DTXSID60363880;(R)-3-hydroxy-1-boc piperidine;AM742;N-BOC-3-(R)-hydroxy-piperidine;BCP08552;AKOS005146098;AKOS005259548;AC-2185;CS-W008719;(R)-1-Boc-3-hydroxypiperidine, 95%;AS-16017;BP-13176;(3R)-1-t-butoxycarbonyl-3-hydroxypiperidine;A3108;B4199;(R)-(-)-N-tert-butoxycarbonyl-3-piperidinol;(r)-n-tert-butoxycarbonyl-3-hydroxypiperidine;EN300-97992;(R)-tert-Butyl3-hydroxypiperidine-1-carboxylate;tert-Butyl(3R)-3-hydroxy-1-piperidincarboxylate;(3R)-1-(tert-Butoxycarbonyl)piperidine-3alpha-ol;(r)-tert butyl-3-hydroxypiperidine-1-carboxylate;(R)-tert-butyl 3-hydroxy-1-piperidinecarboxylate;tert-Butyl (3R)-3-hydroxy-1-piperidincarboxylate;tert-butyl (3R)-3-hydroxypiperidin-1-carboxylate;Q-102972;(R)-3-hydroxypiperidine-1-carboxylic acid t-butyl ester;tert-butyl (3r)-3-hydroxyhexahydro-1-pyridinecarboxylate;(R)-3-hydroxy-piperidine carboxylic acid tert-butyl ester;(R)-3-hydroxy-piperidine-carboxylic acid tert-butyl ester;(R)-3-Hydroxypiperidine-1-carboxylic acid tert-butyl ester;1,1-Dimethylethyl (3R)-3-hydroxypiperidine-1-carboxylate;(R)-(+)-3-hydroxypiperidine-1-carboxylic acid tert-butyl ester;3-Hydroxy-piperidine-1-carboxylic acid tert-butyl ester;(R)-1-N-BOC-3-HYDROXYPIPERIDINE

Suppliers and Price of (R)-1-Boc-3-hydroxypiperidine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (R)-1-Boc-3-hydroxypiperidine
  • 25g
  • $ 695.00
  • TRC
  • (R)-1-Boc-3-hydroxypiperidine
  • 2.5g
  • $ 110.00
  • TCI Chemical
  • (R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine >98.0%(GC)
  • 5g
  • $ 113.00
  • TCI Chemical
  • (R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine >98.0%(GC)
  • 1g
  • $ 38.00
  • SynQuest Laboratories
  • (3R)-3-Hydroxypiperidine, N-Boc protected
  • 1 g
  • $ 16.00
  • SynQuest Laboratories
  • (3R)-3-Hydroxypiperidine, N-Boc protected
  • 5 g
  • $ 21.00
  • SynQuest Laboratories
  • (3R)-3-Hydroxypiperidine, N-Boc protected
  • 25 g
  • $ 77.00
  • Sigma-Aldrich
  • (R)-1-Boc-3-hydroxypiperidine 95%
  • 1g
  • $ 98.40
  • Medical Isotopes, Inc.
  • (R)-tert-Butyl3-hydroxypiperidine-1-carboxylate
  • 5 g
  • $ 394.00
  • Matrix Scientific
  • (R)-1-Boc-3-hydroxypiperidine
  • 25g
  • $ 68.00
Total 146 raw suppliers
Chemical Property of (R)-1-Boc-3-hydroxypiperidine Edit
Chemical Property:
  • Vapor Pressure:0.000198mmHg at 25°C 
  • Melting Point:43-50 °C 
  • Refractive Index:1.495 
  • Boiling Point:292.3 °C at 760 mmHg 
  • PKA:14.74±0.20(Predicted) 
  • Flash Point:130.6 °C 
  • PSA:49.77000 
  • Density:1.107 g/cm3 
  • LogP:1.31610 
  • Storage Temp.:2-8°C 
  • Solubility.:soluble in Methanol 
  • XLogP3:1
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:2
  • Exact Mass:201.13649347
  • Heavy Atom Count:14
  • Complexity:210
Purity/Quality:

99% up by HPLC *data from raw suppliers

(R)-1-Boc-3-hydroxypiperidine *data from reagent suppliers

Safty Information:
  • Pictogram(s): Toxic
  • Hazard Codes:
  • Statements: 36/37/38-41-37/38-25 
  • Safety Statements: 26-36/37/39-45 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)(C)OC(=O)N1CCCC(C1)O
  • Isomeric SMILES:CC(C)(C)OC(=O)N1CCC[C@H](C1)O
  • Uses (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.
Technology Process of (R)-1-Boc-3-hydroxypiperidine

There total 39 articles about (R)-1-Boc-3-hydroxypiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 72h;
Guidance literature:
With sodium carbonate; In dichloromethane; water; for 21h; Product distribution / selectivity;
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