N-Tetradecanoylvaline

Base Information

• Chemical Name: N-Tetradecanoylvaline
• CAS No.: 14379-30-7
• Molecular Formula: C19H37 N O3
• Molecular Weight: 327.508
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID90607507
• Mol file: 14379-30-7.mol

Synonyms:N-Tetradecanoylvaline;14379-30-7;3-methyl-2-(tetradecanoylamino)butanoic acid;3-methyl-2-(1-oxotetradecylamino)butanoic acid;N-Tetradecanoyl-L-valine;N-Myristoyl Valine;SCHEMBL9666571;DTXSID90607507;A808108

Chemical Property of N-Tetradecanoylvaline

Chemical Property:

• PSA: 66.40000
• LogP: 5.30380
• XLogP3: 6.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 15
• Exact Mass: 327.27734404
• Heavy Atom Count: 23
• Complexity: 316

Purity/Quality:

98% ^*data from raw suppliers

N-TETRADECANOYL-L-VALINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCC(=O)NC(C(C)C)C(=O)O
• Uses: suzuki reaction

Technology Process of N-Tetradecanoylvaline

There total 7 articles about N-Tetradecanoylvaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C20H39NO3 (1052696-18-0) → N-tetradecanoyl-valine* (14379-30-7)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1039/c6tb02192a

Reference yield: 96.0%

N-succinimidyl myristate (69888-86-4) + L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) → N-tetradecanoyl-valine* (14379-30-7)

Guidance literature:

With triethylamine; In ethanol; water; at 60 - 80 ℃; for 20h;

DOI:10.1039/c5ra10209j

Reference yield:

L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) + tetradecanoyl chloride (112-64-1) → N-tetradecanoyl-valine* (14379-30-7)

Guidance literature:

With sodium hydroxide; In water; acetone; at 0 - 25 ℃; pH=Ca. 9;

DOI:10.1007/s11696-018-0614-4

upstream raw materials:

C₂₀H₃₉NO₃

N-succinimidyl myristate

L-valine

n-tetradecanoic acid

Refernces

• 1、 Janni, D. Sirisha,Reddy, U. Chandrasekhar,Saroj, Soumya,Muraleedharan. "A modular approach towards drug delivery vehicles using oxanorbornane-based non-ionic amphiphiles". supporting information. p. 8025 - 8032. Retrieved 2016/12/18.
• 2、 Basak, Shibaji,Nanda, Jayanta,Banerjee, Arindam. "Multi-stimuli responsive self-healing metallo-hydrogels: Tuning of the gel recovery property". supporting information. p. 2356 - 2359. Retrieved 2014/03/21.