3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride

Base Information

• Chemical Name: 3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride
• CAS No.: 70458-22-9
• Molecular Formula: C₁₂H₁₁ClO₄
• Molecular Weight: 254.67
• Mol file: 70458-22-9.mol

Synonyms:3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride

Chemical Property of 3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride

There total 2 articles about 3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopropylacetyl chloride (54322-65-5) + 3-chloro-benzenecarboperoxoic acid (937-14-4) → 3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride (70458-22-9)

Guidance literature:

With pyridine; In hexane;

DOI:10.1021/ja00502a026

Reference yield:

cyclopropylacetic acid (5239-82-7) → 3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride (70458-22-9)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 25 °C

2: pyridine / diethyl ether / 1 h / -15 °C

With pyridine; oxalyl dichloride; N,N-dimethyl-formamide; In diethyl ether; dichloromethane;

DOI:10.1021/acs.orglett.9b04218

Reference yield:

3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride (70458-22-9) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 4-<4-(N,N-Dimethylamino)benzyl>-N-methylaniline (53477-27-3) + 4,4'-methylene-bis(N,N-dimethylaniline) (101-61-1)

Guidance literature:

In chloroform; at -40 ℃; for 2h;

DOI:10.1021/jo00293a021

upstream raw materials:

cyclopropylacetyl chloride

3-chloro-benzenecarboperoxoic acid

cyclopropylacetic acid

Downstream raw materials:

2-Cyclopropylmethyl-N¹,N¹,N⁴,N⁴-tetramethyl-benzene-1,4-diamine

2-But-3-enyl-N¹,N¹,N⁴,N⁴-tetramethyl-benzene-1,4-diamine

4-<4-(N,N-Dimethylamino)benzyl>-N-methylaniline

4,4'-methylene-bis(N,N-dimethylaniline)

Refernces

• 1、 Taylor,Govindan,Kaelin. "RADICAL AND IONIC REACTION PATHWAYS IN THE THERMAL DECOMPOSITION OF DIACYL PEROXIDES1.". . p. 2091 - 2099. Retrieved 2007/10/12.