Boc-3-(4-Biphenylyl)-D-alanine

Base Information Edit

Chemical Name:Boc-3-(4-Biphenylyl)-D-alanine
CAS No.:128779-47-5
Molecular Formula:C20H23NO4
Molecular Weight:341.407
Hs Code.:2922498590
European Community (EC) Number:852-973-3
DSSTox Substance ID:DTXSID20427078
Nikkaji Number:J3.457.620C
Wikidata:Q72448709
Mol file:128779-47-5.mol

Synonyms:128779-47-5;BOC-D-4,4'-BIPHENYLALANINE;Boc-3-(4-Biphenylyl)-D-alanine;Boc-D-4,4-Biphenylalanine;(R)-3-([1,1'-BIPHENYL]-4-YL)-2-((TERT-BUTOXYCARBONYL)AMINO)PROPANOIC ACID;BOC-D-4-PHENYLPHENYLALANINE;BOC-4-BIPHENYL-D-ALA;(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoic acid;BOC-D-BPH-OH;BOC-P-PHENYL-D-PHENYLALANINE;SCHEMBL1326276;DTXSID20427078;NBVVKAUSAGHTSU-QGZVFWFLSA-N;BCP14591;N-Boc-3-(4-biphenylyl)-D-alanine;MFCD00191185;(2R)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-phenylphenyl)propanoic acid;AKOS016842314;AC-9870;AM85544;CS-W023100;DS-1074;EN300-3404696;A805862;(R)-3-biphenyl-4-yl-2-t-butoxycarbonylamino-propionic acid;(R)-3-(4-Biphenylyl)-2-(tert-butyloxycarbonylamino)propionic acid;(R)-3-([1,1'-BIPHENYL]-4-YL)-2-(BOC-AMINO)PROPANOIC ACID;(R)-3-(BIPHENYL-4-YL)-2-(TERT-BUTOXYCARBONYLAMINO)PROPANOIC ACID;(2R)-3-(BIPHENYL-4-YL)-2-[(TERT-BUTOXYCARBONYL)AMINO]PROPANOIC ACID;(2R)-3-{[1,1'-biphenyl]-4-yl}-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;(R)-3-([1,1'-BIPHENYL]-4-YL)-2-((TERT-BUTOXYCARBONYL)AMINO)PROPANOICACID;[1,1'-Biphenyl]-4-propanoic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-, (alphaR)-;(2R)-3-([1,1'-Biphenyl]-4-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid (non-preferred name);2-(tert-butoxycarbonylamino)-3-(4-phenylphenyl)propanoic acid;(R)-3-([1,1'-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid

Suppliers and Price of Boc-3-(4-Biphenylyl)-D-alanine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Boc-D-4,4''-biphenylalanine
1g
$ 95.00

Matrix Scientific
Boc-D-4,4-Biphenylalanine 95+%
1g
$ 44.00

Matrix Scientific
Boc-D-4,4-Biphenylalanine 95+%
5g
$ 125.00

Matrix Scientific
Boc-D-4,4-Biphenylalanine 95+%
10g
$ 200.00

Iris Biotech GmbH
Boc-D-Bip-OH
1 g
$ 243.00

Crysdot
(R)-3-([1,1'-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoicacid 95+%
100g
$ 970.00

Crysdot
(R)-3-([1,1'-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoicacid 95+%
25g
$ 303.00

ChemScene
[1,1'-Biphenyl]-4-propanoicacid,α-[[(1,1-dimethylethoxy)carbonyl]amino]-,(αR)- 99.43%
5g
$ 63.00

ChemScene
[1,1'-Biphenyl]-4-propanoicacid,α-[[(1,1-dimethylethoxy)carbonyl]amino]-,(αR)- 99.43%
10g
$ 113.00

chempep
Boc-D-4,4'-Biphe-OH
5g
$ 160.00

Total 82 raw suppliers

Chemical Property of Boc-3-(4-Biphenylyl)-D-alanine Edit

Chemical Property:

Vapor Pressure:6.31E-11mmHg at 25°C
Refractive Index:1.562
Boiling Point:528.2 °C at 760 mmHg
PKA:3.88±0.10(Predicted)
Flash Point:273.2 °C
PSA：75.63000
Density:1.161 g/cm³
LogP:4.26490
Storage Temp.:Store at RT.
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:341.16270821
Heavy Atom Count:25
Complexity:443

Purity/Quality:

99.5% ^*data from raw suppliers

Boc-D-4,4''-biphenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)C2=CC=CC=C2)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)C(=O)O

Technology Process of Boc-3-(4-Biphenylyl)-D-alanine

There total 41 articles about Boc-3-(4-Biphenylyl)-D-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: C₁₅H₁₅NO₂*ClH

: 128779-47-5
(2R)-3-(biphenyl-4-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 18h;

Reference yield: 98.0%

: 62129-39-9,79561-82-3
4-bromo-N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-phenylalanine

: 98-80-6
phenylboronic acid

: 119273-61-9,128779-47-5,147923-08-8
N-tert-butoxycarbonyl-p-phenyl-L-phenylalanine

Guidance literature:: With dipotassium hydrogenphosphate; formic acid; Pd(OAc)2(2-amino-4,6-dihydroxypyrimidine disodium salt)2; In water; at 37 ℃; for 4h;
DOI:10.1021/ja907150m

Reference yield: 95.0%

: 103882-09-3,62129-44-6
N-Boc-4-I-Phe-OH

: 98-80-6
phenylboronic acid

: 119273-61-9,128779-47-5,147923-08-8
N-tert-butoxycarbonyl-p-phenyl-L-phenylalanine

Guidance literature:: With dipotassium hydrogenphosphate; formic acid; Pd(OAc)2(2-amino-4,6-dihydroxypyrimidine disodium salt)2; In water; at 37 ℃; for 4h;
DOI:10.1021/ja907150m