2-Chloromethyl-4,6-dimethoxypyrimidine

Base Information

• Chemical Name: 2-Chloromethyl-4,6-dimethoxypyrimidine
• CAS No.: 114108-86-0
• Molecular Formula: C7H9ClN2O2
• Molecular Weight: 188.614
• Hs Code.: 2933599590
• European Community (EC) Number: 801-585-2
• DSSTox Substance ID: DTXSID10450037
• Nikkaji Number: J1.038.976C
• Wikidata: Q72453898
• Mol file: 114108-86-0.mol

Synonyms:2-Chloromethyl-4,6-dimethoxypyrimidine;114108-86-0;2-(chloromethyl)-4,6-dimethoxypyrimidine;2-(Chloromethyl)-4,6-dimethoxy;2-Chloromethyl-4,6-dimethoxy-pyrimidine;2-Chloromethyl-4,6-dimethoxylpymidine;SCHEMBL379405;DTXSID10450037;BWCCPOQIMGGGQX-UHFFFAOYSA-N;AMY11040;MFCD00274539;AKOS006229045;AB05878;AC-26651;PS-11631;A2322;FT-0642780;J-509031

Chemical Property of 2-Chloromethyl-4,6-dimethoxypyrimidine

Chemical Property:

• Appearance/Colour: white powder
• Vapor Pressure: 0.011mmHg at 25°C
• Melting Point: 39-42 °C
• Refractive Index: 1.513
• Boiling Point: 270.952 °C at 760 mmHg
• PKA: 0.43±0.30(Predicted)
• Flash Point: 117.668 °C
• PSA: 44.24000
• Density: 1.244 g/cm³
• LogP: 1.23260
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 188.0352552
• Heavy Atom Count: 12
• Complexity: 125

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloromethyl-4,6-dimethoxypyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi， T
• Hazard Codes: Xi,T
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=NC(=N1)CCl)OC
• Uses: Intermediate fr life science products Attributes For further information please contact us Contact

Technology Process of 2-Chloromethyl-4,6-dimethoxypyrimidine

There total 1 articles about 2-Chloromethyl-4,6-dimethoxypyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-(chloromethyl)-4,6-dimethoxypyrimidine (114108-86-0)

Guidance literature:

Reference yield: 53.0%

2-(chloromethyl)-4,6-dimethoxypyrimidine (114108-86-0) → C25H30N4O5S3

Guidance literature:

(R)-3-cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-(5-thiocyanato-thiazol-2-yl)-propionamide; With sodium tetrahydroborate; In ethanol; at 0 ℃; for 1h;

2-(chloromethyl)-4,6-dimethoxypyrimidine; In ethanol; acetone; at 20 ℃; for 18h;

Reference yield:

1-t-butoxycarbonyl-4-phenyl-4-hydroxymethyl piperidine (158144-85-5) + 2-(chloromethyl)-4,6-dimethoxypyrimidine (114108-86-0) → C24H33N3O5 (1175065-56-1)

Guidance literature:

Downstream raw materials:

C₂₄H₃₃N₃O₅

Refernces