Nonafluoropentanoyl chloride

Base Information

• Chemical Name: Nonafluoropentanoyl chloride
• CAS No.: 375-60-0
• Molecular Formula: C5ClF9O
• Molecular Weight: 282.493
• Hs Code.: 2915900090
• European Community (EC) Number: 836-689-7
• DSSTox Substance ID: DTXSID90379717
• Nikkaji Number: J2.073.601A
• Wikidata: Q82169655
• Mol file: 375-60-0.mol

Synonyms:Nonafluoropentanoyl chloride;375-60-0;Nonafluoropentanoylchloride;2,2,3,3,4,4,5,5,5-nonafluoropentanoyl Chloride;perfluorovaleroyl chloride;SCHEMBL423737;Nonafluorovaleric acid chloride;DTXSID90379717;HRBNMYUNLLWPAX-UHFFFAOYSA-N;MFCD00155890;AKOS015852691;Nonafluoropentanoyl chloride, AldrichCPR;MS-20317;FT-0632058;A823757;2,2,3,3,4,4,5,5,5-nonakis(fluoranyl)pentanoyl chloride

Chemical Property of Nonafluoropentanoyl chloride

Chemical Property:

• Vapor Pressure: 152mmHg at 25°C
• Refractive Index: 1.298
• Boiling Point: 66.4 °C at 760 mmHg
• PSA: 17.07000
• Density: 1.673 g/cm³
• LogP: 3.22000
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 281.9493958
• Heavy Atom Count: 16
• Complexity: 293

Purity/Quality:

99% ^*data from raw suppliers

NonafluoropentanoylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C,Xn
• Statements: 34-36/37/38-22
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

• Canonical SMILES: C(=O)(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)Cl

Technology Process of Nonafluoropentanoyl chloride

There total 3 articles about Nonafluoropentanoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Perfluoropentanoic acid (2706-90-3) → perfluorovaleryl chloride (375-60-0)

Guidance literature:

With phosphorus pentachloride;

DOI:10.1021/ja01118a044

Reference yield:

Perfluoro pentanoyl fluoride (375-62-2) → perfluorovaleryl chloride (375-60-0)

Guidance literature:

With lithium tetrachloroaluminate; for 4h; Heating;

Reference yield:

Perfluoro pentanoyl fluoride (375-62-2) → perfluorovaleryl chloride (375-60-0) + 2,2,3,3,4,4,5,5,5-Nonafluoro-pentanoyl bromide

Guidance literature:

With KAlBr₃Cl; for 4h; Product distribution; Mechanism; Heating; further perfluoroacyl fluorides, further reagents: KAlBr₃F, KAlBr₄, LiAlCl₄, NaAlCl₄, AgAlCl₄, KAlCl₄, RbAlCl₄, CsAlCl₄, NH₄AlCl₄, other complexes of aluminum halides, reaction inhibition by hydrogen halides;

upstream raw materials:

Perfluoropentanoic acid

Perfluoro pentanoyl fluoride

Downstream raw materials:

2,2,3,3,4,4,5,5,5-nonafluoro-1-( p-tolyl)pentan-1-one

Perfluoro pentanoyl fluoride

2,2,3,3,4,4,5,5,5-nonafluoro-N-[4-(cyanomethyl)phenyl]pentanamide

2,2,3,3,4,4,5,5,5-nonafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phenyl]pentanamide

Refernces

• 1、 Granados, Alejandro,De Rossi, Rita H.. "Multiple pathways in cyclodextrin-catalyzed hydrolysis of perfluoroalkylamides". . p. 3690 - 3696. Retrieved 2007/10/02.